SESQUITERPENE

Sesquiterpene having three isoprene units is a kind of terpene , whose general formula is CH, most of them are in line with isoprene rule. Sesquiterpene compounds widely distributed, most abundant in Magnoliales, rue mesh, cornales and asterales (asterales) plants. Generally speaking, sesquiterpene presents in volatile oil in the form of oxygen-containing derivativesthe , such as alcohols, ketones and lactones, the main composition of volatile oil in the high-boiling part , have a strong aroma and biological activity, are pharmaceutical, food, cosmetics important raw material for industry.

Sesquiterpene compounds, in terms of the number or type of structure from the point of view of the skeleton are the largest one in terpenoids. Sesquiterpene are classified by the number of  carbon ring on their structure , for example, acyclic, monocyclic, bicyclic, tricyclic and tetracyclic and so on. Also classified according to the size of the ring, such as five, six, seven till eleven membered ring. If it is classified according to containing group in its structure, it is easy to recognize their physicochemical properties and physiological activities, such as sesquiterpene alcohols, aldehydes, lactones and so on.

The following are some common sesquiterpene compound:
(1) Farnesol ,an open-chain sesquiterpene, presents in aromatic plants volatile oil such as lemongrass, orange blossom, rose and others. Farnesol as a colorless oily liquid, is a valuable spice. having insect juvenile hormone activity. Once the amount of the insect juvenile hormone excess, it will inhibit the insect metamorphosis and maturity.
(2)Germacrone, Aka Big geranylflavanone ketone, presents in the volatile oil of Xing'an azalea (rhododendron) leaves, is a ten-member ring monocyclic sesquiterpene. Rhododendron volatile oil has the effect of treating cough, phlegm, asthma and are useful for the treatment of chronic bronchitis, cuckoo ketone ,whose melting point is 56 ~ 57 ℃,is the main component .
(3) Gguaiazulene. a sesquiterpene ingredients, presents in the tribulus plants guaiac volatile oil, volatile oil Geranium.
guaiazulene. a blue needle crystallization,whose melting point is 31 ℃, has anti-inflammatory effect, promoting wound healing. It is one of the main components of  domestic burn ointment.

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Structure Chemical Name CAS MF
Sulfocostulide A Sulfocostulide A 1016983-51-9 C15H20O5S
Apocynol A Apocynol A 358721-33-2 C13H20O3
COSTIC ACID COSTIC ACID 3650-43-9 C15H22O2
4,5-Dihydroblumel A 4,5-Dihydroblumel A 155418-97-6 C13H22O3
6,8-Cyclo-1,4-eudesmanediol 6,8-Cyclo-1,4-eudesmanediol 213769-80-3 C15H26O2
Arteannuin N Arteannuin N 207446-92-2 C15H22O3
Chlorahololide D Chlorahololide D 943136-39-8 C38H44O11
Macrocarpal B Macrocarpal B 142698-60-0 C28H40O6
Macrocarpal L Macrocarpal L 327601-97-8 C28H40O6
Shizukalide H Shizukalide H 1136932-34-7 C17H20O5
Canusesnol A Canusesnol A 816456-90-3 C15H22O3
macrocarpal I macrocarpal I 179388-54-6 C28H42O7
corchoionoside C corchoionoside C 185414-25-9 C19H30O8
macrocarpal H macrocarpal H 179388-53-5 C28H40O6
(-)-Humulene epoxide II (-)-Humulene epoxide II 19888-34-7 C15H24O
Isodeoxyelephantopin Isodeoxyelephantopin 38927-54-7 C19H20O6
13-O-Acetylcorianin 13-O-Acetylcorianin 108887-44-1 C17H20O7
5-Acetoxy-4-[[(2,3-dimethyloxiran-2-yl)carbonyl]oxy]-2,3,3a,4,5,8,9,11a-octahydro-10-methyl-3-methylene-2-oxocyclodeca[b]furan-6-carboxylic acid methyl ester 5-Acetoxy-4-[[(2,3-dimethyloxiran-2-yl)carbonyl]oxy]-2,3,3a,4,5,8,9,11a-octahydro-10-methyl-3-methylene-2-oxocyclodeca[b]furan-6-carboxylic acid methyl ester 24694-79-9 C23H28O9
Leucodin Leucodin 17946-87-1 C15H18O3
6,9,10-Trihydroxy-7-megastigmen-3-one 6,9,10-Trihydroxy-7-megastigmen-3-one 476682-97-0 C13H22O4
7-Megastigmene-3,5,6,9-tetrol 7-Megastigmene-3,5,6,9-tetrol 276870-26-9 C13H24O4
Glochicoccin D Glochicoccin D 927812-23-5 C21H24O10
12-HydroxyisodriMenin 12-HydroxyisodriMenin 218780-16-6 C15H22O3
6-O-Acetylcoriatin 6-O-Acetylcoriatin 1432063-63-2 C17H22O7
Chlorantholide D Chlorantholide D 1253106-58-9 C15H18O4
Deacetyleupaserrin Deacetyleupaserrin 38456-39-2 C20H26O6
Arteannuin L Arteannuin L 207446-89-7 C15H22O3
Ilicol Ilicol 72715-02-7 C15H26O2
Shizukolidol Shizukolidol 90332-92-6 C15H20O3
11R,12-Dihydroxyspirovetiv-1(10)-en-2-one 11R,12-Dihydroxyspirovetiv-1(10)-en-2-one 62574-30-5 C15H24O3
DeMethylsonchifolin DeMethylsonchifolin 956384-55-7 C20H24O6
Onitisin 2'-O-glucoside Onitisin 2'-O-glucoside 62043-53-2 C21H30O9
DehydrochroMolaenin DehydrochroMolaenin 20013-76-7 C15H14O
Shizukanolide F Shizukanolide F 120061-96-3 C15H18O4
4-Hydroxy-11,12,13-trinor-5-eudesMen-7-one 4-Hydroxy-11,12,13-trinor-5-eudesMen-7-one 133369-42-3 C12H18O2
10(14)-Cadinene-4,11-diol 10(14)-Cadinene-4,11-diol 658062-23-8 C15H26O2
8α-(2-Methylacryloyloxy)
hirsutinolide 13-O-acetate 8α-(2-Methylacryloyloxy) hirsutinolide 13-O-acetate 67667-71-4 C21H26O8
trans-Norpterosin C trans-Norpterosin C 64890-70-6 C13H16O3
loliolide loliolide 5989-02-6 C11H16O3
torilin torilin 13018-10-5 C22H32O5
(4R)-4,4a,5,6,7,8-Hexahydro-4β-hydroxy-1,4aβ-dimethyl-7β-(1-methylethenyl)naphthalen-2(3H)-one (4R)-4,4a,5,6,7,8-Hexahydro-4β-hydroxy-1,4aβ-dimethyl-7β-(1-methylethenyl)naphthalen-2(3H)-one 105108-20-1 C15H22O2
(4aR)-4a,5,6,7,8,8a-Hexahydro-4aα-hydroxy-6α-isopropenyl-4,8aα-dimethylnaphthalene-2(1H)-one (4aR)-4a,5,6,7,8,8a-Hexahydro-4aα-hydroxy-6α-isopropenyl-4,8aα-dimethylnaphthalene-2(1H)-one 24405-57-0 C15H22O2
1,3,5-Cadinatriene-3,8-diol 1,3,5-Cadinatriene-3,8-diol 941227-27-6 C15H22O2
DriM-7-ene-11,12-diol acetonide DriM-7-ene-11,12-diol acetonide 213552-47-7 C18H30O2
8α-Methacryloyloxybalchanin 8α-Methacryloyloxybalchanin 104021-39-8 C19H24O5
Chlorantholide C Chlorantholide C 1372558-35-4 C15H18O3
Epiguajadial B Epiguajadial B 1411629-26-9 C30H34O5
7α-Hydroxy-4,11-cadinadiene-3,8-dione 7α-Hydroxy-4,11-cadinadiene-3,8-dione 1423809-64-6 C15H20O3
1α-Hydroxytorilin 1α-Hydroxytorilin 887147-75-3 C22H32O6
Diacetylpiptocarphol Diacetylpiptocarphol 101628-29-9 C19H24O9
6,7-Dihydro-1,5,8-trimethylnaphtho[2,1-b]furan 6,7-Dihydro-1,5,8-trimethylnaphtho[2,1-b]furan 20013-75-6 C15H16O
(2S,3S)-2,3-Dihydro-3-hydroxy-6-(2-hydroxyethyl)-2,5,7-trimethyl-1H-inden-1-one (2S,3S)-2,3-Dihydro-3-hydroxy-6-(2-hydroxyethyl)-2,5,7-trimethyl-1H-inden-1-one 35938-43-3 C14H18O3
10(14)-Cadinene-4,5-diol 10(14)-Cadinene-4,5-diol 672336-50-4 C15H26O2
3-Acetoxy-4,7(11)-cadinadien-8-one 3-Acetoxy-4,7(11)-cadinadien-8-one 104975-02-2 C17H24O3
4,5-Diepipsidial A 4,5-Diepipsidial A 1219603-97-0 C30H34O5
Pterolactone A Pterolactone A 74730-10-2 C15H16O4
Cycloshizukaol A Cycloshizukaol A 150033-85-5 C32H36O8
ChloraMultilide C ChloraMultilide C 1000995-48-1 C39H42O14
8-O-Acetyltorilolone 8-O-Acetyltorilolone 20482-21-7 C17H26O4
8α-Tigloyloxyhirsutinolide 13-O-acetate 8α-Tigloyloxyhirsutinolide 13-O-acetate 83182-58-5 C22H28O8
2(3H)-Naphthalenone, 4,4a,5,6,7,8-hexahydro-7,8-dihydroxy-4a,8-dimethyl-, (4aR,7R,8R)- (9CI) 2(3H)-Naphthalenone, 4,4a,5,6,7,8-hexahydro-7,8-dihydroxy-4a,8-dimethyl-, (4aR,7R,8R)- (9CI) 363610-34-8 C12H18O3
Methyl isocostate Methyl isocostate 132342-55-3 C16H24O2
3,11,12-Trihydroxyspirovetiv-1(10)-en-2-one 3,11,12-Trihydroxyspirovetiv-1(10)-en-2-one 220328-03-0 C15H24O4
Chlorantholide E Chlorantholide E 1372558-36-5 C15H18O5
MegastigM-7-ene-3,4,6,9-tetrol MegastigM-7-ene-3,4,6,9-tetrol 180164-14-1 C13H24O4
8β-Tigloyloxycostunolide 8β-Tigloyloxycostunolide 96850-21-4 C20H26O4
Bakkenolide Db Bakkenolide Db 226711-23-5 C21H28O7S
GerMacrone 4,5-epoxide GerMacrone 4,5-epoxide 92691-35-5 C15H22O2
eupatoriopicrine eupatoriopicrine 6856-01-5 C20H26O6
(2R)-Pterosin B (2R)-Pterosin B 34175-96-7 C14H18O2
3-O-Methyltagitinin F 3-O-Methyltagitinin F 110382-37-1 C20H26O6
4(15)-Oppositene-1,7-diol 4(15)-Oppositene-1,7-diol 640289-58-3 C15H26O2
4-Epi-isoinuviscolide 4-Epi-isoinuviscolide 68832-39-3 C15H20O3
11S,12-Dihydroxyspirovetiv-1(10)-en-2-one 11S,12-Dihydroxyspirovetiv-1(10)-en-2-one 62623-86-3 C15H24O3
Epipterosin L 2'-O-glucoside Epipterosin L 2'-O-glucoside 61117-89-3 C21H30O9
Isoscabertopin Isoscabertopin 439923-16-7 C20H22O6
8'-Oxo-6-hydroxydihydrophaseic acid 8'-Oxo-6-hydroxydihydrophaseic acid 1388075-44-2 C15H20O7
Torilolone Torilolone 13018-09-2 C15H24O3
1β-Hydroxytorilin 1β-Hydroxytorilin 509078-16-4 C22H32O6
1-Oxobakkenolide S 1-Oxobakkenolide S 18456-02-5 C15H20O4
8α-(2-Methylacryloyloxy)hirsutinolide 8α-(2-Methylacryloyloxy)hirsutinolide 188293-70-1 C19H24O7
Eupaglehnin C Eupaglehnin C 476630-49-6 C20H26O5
8alpha-Hydroxy-alpha-gurjunene 8alpha-Hydroxy-alpha-gurjunene 70206-70-1 C15H24O
alpha-Epoxydihydroartemisinic acid alpha-Epoxydihydroartemisinic acid 380487-65-0 C15H24O3
11,13-Dihydroivalin 11,13-Dihydroivalin 150150-61-1 C15H22O3
Scabertopin Scabertopin 185213-52-9 C20H22O6
Chloroenhydrin Chloroenhydrin 38230-99-8 C23H29ClO10
8β-(2-Hydroxy-2-Methyl
-3-oxobutyryloxy)glucozaluzanin C 8β-(2-Hydroxy-2-Methyl -3-oxobutyryloxy)glucozaluzanin C 93395-31-4 C26H34O12
ChartarlactaM A ChartarlactaM A 1528745-88-1 C23H29NO5
Eupatolide Eupatolide 6750-25-0 C15H20O3
S-Fukinolide S-Fukinolide 18456-03-6 C21H28O6S
(1aR,4E,10aR)-1a,3,6,10a-Tetrahydro-1a,5,9-trimethyloxireno[4,5]cyclodeca[1,2-b]furan-10(2H)-one (1aR,4E,10aR)-1a,3,6,10a-Tetrahydro-1a,5,9-trimethyloxireno[4,5]cyclodeca[1,2-b]furan-10(2H)-one 7727-79-9 C15H18O3
[R,(-)]-2,3-Dihydro-3-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetramethyl-1H-indene-1-one [R,(-)]-2,3-Dihydro-3-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetramethyl-1H-indene-1-one 34169-70-5 C15H20O3
3-Acetoxy-4-cadinen-8-one 3-Acetoxy-4-cadinen-8-one 923950-05-4 C17H26O3
Reneilmol Reneilmol 260968-11-4 C15H28O3
Pterosin D 3-O-glucoside Pterosin D 3-O-glucoside 84299-80-9 C21H30O8
3,11,12-Trihydroxyspirovetiv-1(10)-en-2-one 3,11,12-Trihydroxyspirovetiv-1(10)-en-2-one 220328-04-1 C15H24O4
15-DihydroepioxylubiMin 15-DihydroepioxylubiMin 129214-59-1 C15H26O3
aristolone aristolone 6831-17-0 C15H22O
(E)-2-Methyl-2-butenoic acid [(1aR,3S,4Z,5aR,8aR,9R,10aR)-1a,2,3,5a,7,8,8a,9,10,10a-decahydro-3-hydroxy-4,10a-dimethyl-8-methylene-7-oxooxireno[5,6]cyclodeca[1,2-b]furan-9-yl] ester (E)-2-Methyl-2-butenoic acid [(1aR,3S,4Z,5aR,8aR,9R,10aR)-1a,2,3,5a,7,8,8a,9,10,10a-decahydro-3-hydroxy-4,10a-dimethyl-8-methylene-7-oxooxireno[5,6]cyclodeca[1,2-b]furan-9-yl] ester 13323-48-3 C20H26O6
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