Amino Acids and Derivatives

Amino acids and their derivatives belong to a compound containing both amino group and carboxyl group. They are presented in both the form of free-state and bound-state in vivo. Free amino acids are distributed in all kinds of animal cells and body fluids with the bound amino acids being the mainly basic components of proteins and peptides.

Natural amino acids act as colorless crystalline materials with relatively high melting points being mostly above 200 ℃. They are usually soluble in water but insoluble in non-polar organic solvents. However, tyrosine and cystine are insoluble in water; proline and hydroxyl proline are soluble in ethanol and ether. All amino acids are soluble in strong acid and alkali solution.

According to the polar characterization of the R group of the side chain of the α-amino acid; those 20 common amino acids that constitute protein can be divided into four groups:
① Amino acids with R group being non-polar; There are 8 kinds in total, wherein five kinds have aliphatic side chains, namely alanine, leucine, isoleucine, valine and proline; two kinds are aromatic amino acids, phenylalanine and tryptophan; one kind belongs to sulfur-containing amino acid, namely methionine; amino acids belonging to this group have lower water solubility than polar R-group amino acid; proline is generally different with α-amino acid, it is formed through the substitution of one hydrogen atom of the amino acid with the side chains of the α- amino acid, belonging actually to imino acid.
② Amino acids with polar but non-charged R group; There are seven kinds in total, namely serine, threonine and tyrosine with R group having hydroxy group; cysteine with R group having a mercapto group of cysteine; glutamine and asparagine with R-group containing amide group, another amino acid is glycine ; glycine molecule has no R group, but having certain polarity, and thus being classified into this group; the side chains in this group of amino acid contain unassociated polar groups and can form hydrogen bonds with water, and is easily soluble in water.
③Amino acids with R group being positively charged amino acids. There are three kinds in total, namely, lysine, arginine, and histidine; they carry positive charge at pH7.0 and are also known as alkaline amino acids.
④Amino acids with R group being negatively charged. There are two kinds in total, namely glutamate and aspartate; at pH7.0, the molecules are negatively charged, also known as acidic amino acids. The formula, abbreviations symbols and related constants of 20 kinds of amino acid structures can be seen from the table. In addition to the 20 common amino acids mentioned above, there are also diiodotyrosine, thyroxine, hydroxyproline and hydroxylysine existing in certain proteins. In addition to amino acids involved in protein composition, it has been also found of more than 200 kinds of other kinds amino acids in a variety of tissues and cells; these amino acids are mostly derivatives of those α- amino acid composition of proteins.

However, there are some β-, γ- or δ- amino acids and some amino acids belong to D-type amino acids such as [beta]-alanine, [gamma]-aminobutyric acid and the phenylalanine contained in the antibiotics gramicidin-S, the D-alanine and D-glutamate contained in Gram-positive bacteria cell wall. Some non-protein amino acids can act as metabolically important precursors or intermediates, wherein β-alanine is the precursors of vitamin pantothenic acid; ornithine, and citrulline are the precursors in the synthesis of arginine; [gamma]-aminobutyric acid is the chemical neurotransmitter. Plants contain a large amount of non-protein amino acids, belonging to plant secondary substances, such as theanine, canavanine, djenkolic acid, β- Cyanoalanine and so on.

In addition to 20 kinds of amino acids found in the body and animal protein products, it has been found of nearly 200 kinds of other kinds of amino acids in nature. Most of them have been discovered in the plant kingdom and have complex molecular structures with no relation with the protein metabolism. There have been less that have been seen in the animal kingdom with some of them being originated from the chemical modification of certain incorporated amino acids in the specific proteins, for example, the proline and lysine contained in collagen protein are often partially subject to re-hydroxylation of hydroxyproline and hydroxylysine; Another example is that there are often a small amount of lysine and histidine contained in actin and myosin protein containing hypermethylated εN methyl-lysine and 3N-histidine; it has been also found in the histone protein that the ∈ amino group contained in lysine is acetylated and the OH group in the serine is phosphorylated; thyroglobulin contains iodinated tyrosine and thyronine iodide; The heavy chain of τ myosin and the N-terminal of certain proteins contain pyroglutamate formed by glutamine; there also exists the cystine constituting of two cysteine molecules in the general protein.

Click on the specific product, view the latest prices of the products, information, serving information
Structure Chemical Name CAS MF
BOC-SAR-OH BOC-SAR-OH 13734-36-6 C8H15NO4
D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT 103404-90-6 C5H9NaO5
N-2-NITROPHENYLSULFENYL-L-ISOLEUCINE DICYCLOHEXYLAMMONIUM SALT N-2-NITROPHENYLSULFENYL-L-ISOLEUCINE DICYCLOHEXYLAMMONIUM SALT 7675-49-2 C24H39N3O4S
POLY-EPSILON-CBZ-L-LYSINE POLY-EPSILON-CBZ-L-LYSINE 25931-47-9 C14H20N2O4
(2S,4S)-FMOC-4-AMINO-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID (2S,4S)-FMOC-4-AMINO-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID C25H28N2O6
BOC-(S)-3-AMINO-3-(4-NITRO-PHENYL)-PROPIONIC ACID BOC-(S)-3-AMINO-3-(4-NITRO-PHENYL)-PROPIONIC ACID 499995-73-2 C14H18N2O6
FMOC-(R)-3-AMINO-3-(3-HYDROXY-PHENYL)-PROPIONIC ACID FMOC-(R)-3-AMINO-3-(3-HYDROXY-PHENYL)-PROPIONIC ACID 511272-35-8 C24H21NO5
DL-ALPHA-METHYLLEUCINE DL-ALPHA-METHYLLEUCINE 144-24-1 C7H15NO2
Z-GAMMA-ABU-OH Z-GAMMA-ABU-OH 5105-78-2 C12H15NO4
PHT-GLY-OSU PHT-GLY-OSU 3397-29-3 C14H10N2O6
7-METHYL-DL-TRYPTOPHAN 7-METHYL-DL-TRYPTOPHAN 17332-70-6 C12H14N2O2
BOC-(R)-3-AMINO-5-HEXYNOIC ACID BOC-(R)-3-AMINO-5-HEXYNOIC ACID 332064-91-2 C11H17NO4
3-TRIFLUOROMETHYL-L-PHENYLALANINE 3-TRIFLUOROMETHYL-L-PHENYLALANINE 122839-48-9 C10H10F3NO2
(S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER (S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 84348-38-9 C11H17NO4
Z-D-DAB(BOC)-OH DCHA Z-D-DAB(BOC)-OH DCHA 214852-61-6 C29H47N3O6
2-AMINO-3-PHENYLBUTANOIC ACID HYDROCHLORIDE 2-AMINO-3-PHENYLBUTANOIC ACID HYDROCHLORIDE 80997-87-1 C10H14ClNO2
N-ME-TYR-OH N-ME-TYR-OH 537-49-5 C10H13NO3
4-Hydroxy-L-isoleucine 4-Hydroxy-L-isoleucine 781658-23-9 C6H13NO3
PTH-ARGININE HYDROCHLORIDE PTH-ARGININE HYDROCHLORIDE 117756-28-2 C13H18ClN5OS
FMOC-D-LYS(Z)-OH FMOC-D-LYS(Z)-OH 110990-07-3 C29H30N2O6
Z-D-ASP(OBZL)-OH Z-D-ASP(OBZL)-OH 5241-62-3 C19H19NO6
H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH 121204-87-3 C109H163N25O32S
Fmoc-N-methyl-O-benzyl-L-threonine Fmoc-N-methyl-O-benzyl-L-threonine 198561-81-8 C27H27NO5
BOC-O-DIBENZYLPHOSPHO-L-SERINE BOC-O-DIBENZYLPHOSPHO-L-SERINE 90013-45-9 C22H28NO8P
N-BOC-ALPHA-METHYL-D-SERINE N-BOC-ALPHA-METHYL-D-SERINE 84311-18-2 C9H17NO5
DL-Aspartic acid potassium salt DL-Aspartic acid potassium salt 14434-35-6 C4H6KNO4
GLYCINE N-PROPYL ESTER HYDROCHLORIDE GLYCINE N-PROPYL ESTER HYDROCHLORIDE 13049-01-9 C5H12ClNO2
H-ALPHA-ME-D-PRO-OH H-ALPHA-ME-D-PRO-OH 63399-77-9 C6H11NO2
O-BENZYL-L-SERINE METHYL ESTER HYDROCHLORIDE O-BENZYL-L-SERINE METHYL ESTER HYDROCHLORIDE 19525-87-2 C11H16ClNO3
BOC-(S)-3-AMINO-(6-PHENYL)-5-HEXENOIC ACID BOC-(S)-3-AMINO-(6-PHENYL)-5-HEXENOIC ACID 270596-44-6 C17H23NO4
NOMEGA-(2-ACETAMIDO-3,4,6-TRI-O-BENZYL-2-DEOXY-BETA-D-GLUCOPYRANOSYL)-NALPHA-(TERT-BUTOXYCARBONYL)-L-ASPARAGINE BENZYL ESTER NOMEGA-(2-ACETAMIDO-3,4,6-TRI-O-BENZYL-2-DEOXY-BETA-D-GLUCOPYRANOSYL)-NALPHA-(TERT-BUTOXYCARBONYL)-L-ASPARAGINE BENZYL ESTER 219968-28-2 C45H53N3O10
L-PROLINE BETA-NAPHTHYLAMIDE HYDROCHLORIDE L-PROLINE BETA-NAPHTHYLAMIDE HYDROCHLORIDE 97216-16-5 C15H17ClN2O
DI-DNP-L-LYSINE DI-DNP-L-LYSINE 1655-49-8 C18H18N6O10
FMOC-D-ARG-OH FMOC-D-ARG-OH 130752-32-8 C21H24N4O4
H-MET-OIPR HCL H-MET-OIPR HCL 85391-05-5 C8H18ClNO2S
FMOC-(R)-3-AMINO-4-(4-FLUORO-PHENYL)-BUTYRIC ACID FMOC-(R)-3-AMINO-4-(4-FLUORO-PHENYL)-BUTYRIC ACID C25H22FNO4
(S)-3-AMINO-4-(4-IODOPHENYL)BUTANOIC ACID HYDROCHLORIDE (S)-3-AMINO-4-(4-IODOPHENYL)BUTANOIC ACID HYDROCHLORIDE 270065-70-8 C10H12INO2
L-LEUCINE ALLYL ESTER P-TOLUENESULFONATE SALT L-LEUCINE ALLYL ESTER P-TOLUENESULFONATE SALT 88224-03-7 C16H25NO5S
(R)-3-AMINO-4-(3-THIENYL)BUTANOIC ACID HYDROCHLORIDE (R)-3-AMINO-4-(3-THIENYL)BUTANOIC ACID HYDROCHLORIDE 269726-91-2 C8H11NO2S
BOC-DAB(ALOC)-OH DCHA BOC-DAB(ALOC)-OH DCHA 327156-92-3 C25H45N3O6
BOC-D-CHA-OH DCHA BOC-D-CHA-OH DCHA 198470-07-4 C26H48N2O4
POLY-L-GLUTAMIC ACID SODIUM SALT POLY-L-GLUTAMIC ACID SODIUM SALT 26247-79-0 C15H23N3O10
FMOC-(S)-3-AMINO-3-(4-METHYL-PHENYL)-PROPIONIC ACID FMOC-(S)-3-AMINO-3-(4-METHYL-PHENYL)-PROPIONIC ACID 479064-99-8 C25H23NO4
N-[3-(2-Furyl)acryloyl]-L-phenylalanyl-glycyl-glycine N-[3-(2-Furyl)acryloyl]-L-phenylalanyl-glycyl-glycine 64967-39-1 C20H21N3O6
Z-DEHYDRO-ALA-OME Z-DEHYDRO-ALA-OME 21149-17-7 C12H13NO4
BOC-D-DAP(Z)-OH DCHA BOC-D-DAP(Z)-OH DCHA 81306-94-7 C28H45N3O6
3-(N-ACETYL-L-CYSTEIN-S-YL) ACETAMINOPHEN, SODIUM SALT 3-(N-ACETYL-L-CYSTEIN-S-YL) ACETAMINOPHEN, SODIUM SALT 52372-86-8 C13H16N2O5S
BOC-(S)-3-AMINO-3-(2,4-DICHLORO-PHENYL)-PROPIONIC ACID BOC-(S)-3-AMINO-3-(2,4-DICHLORO-PHENYL)-PROPIONIC ACID 499995-81-2 C14H17Cl2NO4
FMOC-THR(GALNAC(AC)3-ALPHA-D)-OH FMOC-THR(GALNAC(AC)3-ALPHA-D)-OH 116783-35-8 C33H38N2O13
Fmoc-Pro-Pro-OH Fmoc-Pro-Pro-OH 129223-22-9 C25H26N2O5
BOC-GLN-ONP BOC-GLN-ONP 15387-45-8 C16H21N3O7
FMOC-D-DAB(ALOC)-OH FMOC-D-DAB(ALOC)-OH 387824-78-4 C23H24N2O6
BZ-PHE-OH BZ-PHE-OH 2566-22-5 C16H15NO3
Pemetrexed disodium hemipentahydrate Pemetrexed disodium hemipentahydrate 357166-30-4 C20H24N5NaO7
Z-D-GLU(OME)-OH Z-D-GLU(OME)-OH 27025-24-7 C14H17NO6
H-ALA-BETA-ALA-OH H-ALA-BETA-ALA-OH 52788-02-0 C6H12N2O3
Prostratin, PKC activator Prostratin, PKC activator 60857-08-1 C22H30O6
N-(TERT-BUTOXYCARBONYL)-L-PROLINE N'-METHOXY-N'-METHYLAMIDE N-(TERT-BUTOXYCARBONYL)-L-PROLINE N'-METHOXY-N'-METHYLAMIDE 115186-37-3 C12H22N2O4
L-ALPHA-(3-THIENYL)GLYCINE L-ALPHA-(3-THIENYL)GLYCINE 1194-87-2 C6H7NO2S
DL-2-AMINO-3-METHYL-1-BUTANOL DL-2-AMINO-3-METHYL-1-BUTANOL 16369-05-4 C5H13NO
N-ACETYL-L-PHENYLALANYL-3,5-DIIODO-L-TYROSINE N-ACETYL-L-PHENYLALANYL-3,5-DIIODO-L-TYROSINE 3786-08-1 C20H20I2N2O5
H-CYS(ACM)-NH2 HCL H-CYS(ACM)-NH2 HCL 88530-32-9 C6H13N3O2S
H-D-GLU(OBZL)-OBZL P-TOSYLATE H-D-GLU(OBZL)-OBZL P-TOSYLATE 19898-41-0 C26H29NO7S
BOC-D-GLU-OME BOC-D-GLU-OME 55227-00-4 C11H19NO6
(BOC-AMINOOXY)ACETIC ACID (BOC-AMINOOXY)ACETIC ACID 42989-85-5 C7H13NO5
BOC-(S)-3-AMINO-3-(3-FLUORO-PHENYL)-PROPIONIC ACID BOC-(S)-3-AMINO-3-(3-FLUORO-PHENYL)-PROPIONIC ACID 500770-72-9 C14H18FNO4
(2R,3R)-2-AMINO-3-PHENYLMETHOXY-1-BUTANOL (2R,3R)-2-AMINO-3-PHENYLMETHOXY-1-BUTANOL 160841-03-2 C11H18ClNO2
H-D-GLU(OBZL)-OBZL HCL H-D-GLU(OBZL)-OBZL HCL 146844-02-2 C19H22ClNO4
GLY-GLY BENZYL ESTER P-TOLUENESULFONATE SALT GLY-GLY BENZYL ESTER P-TOLUENESULFONATE SALT 1738-82-5 C18H22N2O6S
N-(Trifluoroacetyl)glycine N-(Trifluoroacetyl)glycine 383-70-0 C4H4F3NO3
FMOC-(S)-3-AMINO-3-(2-METHYL-PHENYL)-PROPIONIC ACID FMOC-(S)-3-AMINO-3-(2-METHYL-PHENYL)-PROPIONIC ACID 501015-26-5 C25H23NO4
D-4-PYRIDYLALANINE D-4-PYRIDYLALANINE 174096-41-4 C8H11ClN2O2
6-CHLORO-L-TRYPTOPHAN 6-CHLORO-L-TRYPTOPHAN 33468-35-8 C11H11ClN2O2
O-Cbz-L-Tyrosine O-Cbz-L-Tyrosine 21106-04-7 C17H17NO5
(AC-CYS-OH)2 (AC-CYS-OH)2 5545-17-5 C10H16N2O6S2
FMOC-D-GLA(OTBU)2-OH FMOC-D-GLA(OTBU)2-OH 111662-65-8 C29H35NO8
3,5-Diiodo-L-tyrosine dihydrate 3,5-Diiodo-L-tyrosine dihydrate 312693-60-0 C9H13I2NO5
EC 1.4.1.9 EC 1.4.1.9 9082-71-7
N-ALPHA-BOC-(R)-2-AMINO-3-(DIMETHYLAMINO)PROPIONIC ACID N-ALPHA-BOC-(R)-2-AMINO-3-(DIMETHYLAMINO)PROPIONIC ACID 110755-32-3 C10H20N2O4
(R)-3-AMINO-4-(2-TRIFLUOROMETHYLPHENYL)BUTANOIC ACID HYDROCHLORIDE (R)-3-AMINO-4-(2-TRIFLUOROMETHYLPHENYL)BUTANOIC ACID HYDROCHLORIDE 269396-76-1 C11H12F3NO2
1-METHYL-D-TRYPTOPHAN 1-METHYL-D-TRYPTOPHAN 110117-83-4 C12H14N2O2
BOC-(R)-2-TETRAHYDROISOQUINOLINE ACETIC ACID BOC-(R)-2-TETRAHYDROISOQUINOLINE ACETIC ACID 332064-64-9 C16H21NO4
DL-THIORPHAN DL-THIORPHAN 76721-89-6 C12H15NO3S
N-Fmoc-N'-Trityl-L-histidine pentafluorophenyl ester N-Fmoc-N'-Trityl-L-histidine pentafluorophenyl ester 109434-24-4 C46H32F5N3O4
BZL-SER-OH BZL-SER-OH 17136-45-7 C10H13NO3
L-3-Pyridylalanine hydrochloride L-3-Pyridylalanine hydrochloride 93960-20-4 C8H11ClN2O2
N-Myristoyl-L-serine sodium salt N-Myristoyl-L-serine sodium salt 142739-82-0 C17H32NNaO4
BOC-D-METHIONINOL BOC-D-METHIONINOL 91177-57-0 C10H21NO3S
FMOC-(S)-3-AMINO-3-(3-CHLORO-PHENYL)-PROPIONIC ACID FMOC-(S)-3-AMINO-3-(3-CHLORO-PHENYL)-PROPIONIC ACID 507472-16-4 C24H20ClNO4
1-N2-[(S)-ETHOXYCARBONYL-3-PHENYLPROPYL]-N6-TRIFLUOROACETYL-L-LYSYL-L-PROLINE 1-N2-[(S)-ETHOXYCARBONYL-3-PHENYLPROPYL]-N6-TRIFLUOROACETYL-L-LYSYL-L-PROLINE C25H34F3N3O6
PHENYLTHIOHYDANTOIN-GLUTAMINE PHENYLTHIOHYDANTOIN-GLUTAMINE 10567-86-9 C12H13N3O2S
H-PHE-LEU-OH H-PHE-LEU-OH 3303-55-7 C15H22N2O3
AC-WEHD-AMC AC-WEHD-AMC 189275-74-9 C38H40N8O11
Z-GLY-GLY-ILE-OH Z-GLY-GLY-ILE-OH 102601-54-7 C18H25N3O6
AC-D-NVA-OH AC-D-NVA-OH 57357-56-9 C7H13NO3
FMOC-ARG(BOC)2-OH FMOC-ARG(BOC)2-OH 143824-77-5 C31H40N4O8
EC 1.4.1.3 EC 1.4.1.3 9029-11-2 NULL
FMOC-(R)-3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID FMOC-(R)-3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID 511272-50-7 C24H20FNO4
BOC-CYS(TBU)-OH BOC-CYS(TBU)-OH 56976-06-8 C12H23NO4S
BOC-D-MEPHE-OH BOC-D-MEPHE-OH 85466-66-6 C15H21NO4
Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.