ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Proline derivatives (S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER

(S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER

(S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Basic information
Product Name:(S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER
Synonyms:1,2-Pyrrolidinedicarboxylicacid, 4-Methylene-, 1-(1,1-diMethylethyl) ester, (2S)-;(S)-1-(tert-butoxycarbonyl)-4-Methylenepyrrolidine-2-carboxylic acid;N-tert-Butoxycarbonyl-4-methylene-L-proline;N-Boc-4-methylene-L-proline 97%;N-T-BOC-4-METHYLENE-L-PROLINE;(S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER;BOC-4-METHYLENE-L-PROLINE;N-Boc-4-methylene-L-proline
CAS:84348-38-9
MF:C11H17NO4
MW:227.26
EINECS:
Product Categories:pharmacetical;Heterocycles
Mol File:84348-38-9.mol
(S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Structure
(S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Chemical Properties
Melting point 110-115 °C
Boiling point 349.9±42.0 °C(Predicted)
density 1.18±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 2-8°C(protect from light)
pka3.80±0.20(Predicted)
optical activity[α]22/D 58°, c = 0.5 in chloroform
Water Solubility Insoluble in water.
CAS DataBase Reference84348-38-9
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 3
HS Code 2933998090
MSDS Information
(S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Usage And Synthesis
UsesAs important intermediates in various areas such as peptide synthesis, asymmetric synthesis, medicinal chemistry, and polymer chemistry. The fluorous prolins were synthesized from commercially available N-Boc-4-methylene- L-proline.
(S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Preparation Products And Raw materials
N-Boc-4-Methylene-L-proline Methyl Ester L-Tryptophan L(+)-Arginine 4-Methylene-1-Boc-D-proline Boc-L-2-allylglycine dicyclohexylamine salt 4,5-DEHYDRO-LEUCINE BOC-DL-METHALLYLGLYCINE (S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 2-amino-4-methyl-pent-4-enoic acid 2-(Tert-Butoxycarbonylamino)Pent-4-Enoic Acid L-Allylglycine TERT-BUTYL N-ALLYLCARBAMATE ETHYL ALLYLFORMYLMETHYLCARBAMATE
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