DIHYDROERGOTAMINE MESYLATE

DIHYDROERGOTAMINE MESYLATE Basic information
Product Name:DIHYDROERGOTAMINE MESYLATE
Synonyms:dihydroergotoxin;dihydro-ergotoxin;DIHYDROERGOTAMINE MESYLATE;DIHYDROERGOTAMINE METHANESULFONATE;DIHYDROERGOTAMINE METHANESULFONATE SALT;Dihydroergotoxine;8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine, ergotoxine deriv.;9,10-Dihydroergotoxine
CAS:11032-41-0
MF:C34H41N5O8S
MW:679.78
EINECS:
Product Categories:
Mol File:11032-41-0.mol
DIHYDROERGOTAMINE MESYLATE Structure
DIHYDROERGOTAMINE MESYLATE Chemical Properties
solubility methanol: 21 mg/mL
form powder
color white
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22
Safety Statements 36
WGK Germany 3
RTECS KE7920000
Toxicitymouse,LD50,subcutaneous,71mg/kg (71mg/kg),Russian Pharmacology and Toxicology Vol. 31, Pg. 53, 1968.
MSDS Information
ProviderLanguage
SigmaAldrich English
DIHYDROERGOTAMINE MESYLATE Usage And Synthesis
OriginatorRedergin,Lek
UsesCognition adjuvant.
Manufacturing ProcessDihydrotoxine is a mixture of three hydrogenated alkaloides of ergot spur. (Claviceps purpurea). 10 g ergotoxine (the mixture of ergocornine, ergocristine, ergocryptine 1:1:1) in 200 ml dioxane and 20 g Pd/BaSO4 were stirred at a H2 pressure 10 atmospheres at 80°C for 5 hours. The catalyst was filtered off, a filtrate was distilled to dryness in vacuum. The residue was in chloroform dissolved and shook with aluminum oxide. The Al2O3 was filtered off, the filtrate was crystallized after adding of hot benzene and cooling. Yield 6-8 g dihydroergotoxine. It crystallized with 1 mol of benzene. MP: 185°C.
Brand nameAlkergot (Sandoz); Circanol(3M Pharmaceuticals); Deapril (Bristol-Myers Squibb);Gerimal (Watson); Hydergine (Novartis).
Therapeutic FunctionVasodilator
DIHYDROERGOTAMINE MESYLATE Preparation Products And Raw materials
Raw materialsERGTOXIN-->PALLADIUM ON STRONTIUM CARBONATE, REDUCED
Cromolyn Disodium Salt DIHYDROERGOTAMINE MESYLATE MIDODRINE DIHYDROERGOTAMINE Methimazole ERGOTAMINE TARTRATE ergotamine dihydroergocristine Dihydroergotamine Mesylate USP,BP,JP,Eur,Ph DIHYDROERGOTAMINE TARTRATE CRYSTALLINE DIHYDROERGOTAMINE MESYLATE DIHYDROERGOCRISTINE MESYLATE

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.