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(R)-N-Glycidylphthalimide

(R)-N-Glycidylphthalimide Basic information
Product Name:(R)-N-Glycidylphthalimide
Synonyms:(R)-(-)-N-(2,3-Epoxypropyl)phthaliMide, ee: 98%;2-[(2R)-oxiran-2-ylmethyl]-1H-isoindol-1,3(2H)-dione;1H-Isoindole-1,3(2H)-dione,2-[(2R)-2-oxiranylMethyl]-;(R)-(-)-N-(2,3-Epoxypropyl)phthaliMide >=99.0% (GC);(R)-2-OXIRANYLMETHYL-ISOINDOLE-1,3-DIONE;(R)-(-)-GLYCIDYL PHTHALIMIDE;(R)-GLYCIDYL PHTHALIMIDE;(R)-(-)-N-(2,3-Epoxypropyl)phthalimide
CAS:181140-34-1
MF:C11H9NO3
MW:203.19
EINECS:629-091-0
Product Categories:N-Substituted Maleimides, Succinimides & Phthalimides;N-Substituted Phthalimides;Oxiranes;Simple 3-Membered Ring Compounds
Mol File:181140-34-1.mol
(R)-N-Glycidylphthalimide Structure
(R)-N-Glycidylphthalimide Chemical Properties
Melting point 101 °C
Boiling point 347.4±15.0 °C(Predicted)
density 1.446±0.06 g/cm3 (20 ºC 760 Torr)
refractive index -10 ° (C=2.2, CHCl3)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka-2.24±0.20(Predicted)
color White
Safety Information
Hazard Codes Xi
Risk Statements 41
Safety Statements 26-39
WGK Germany 2
HS Code 29251900
MSDS Information
(R)-N-Glycidylphthalimide Usage And Synthesis
Chemical PropertiesWhite solid
Uses(R)-(-)-N-(2,3-Epoxypropyl)phthalimide may be used in the preparation of the following potential chiral solvating agents:
  • 2-[(2R)-2-hydroxy-3-[[(1R)-2-hydroxy-1-phenyl-ethyl]amino]propyl] isoindoline-1,3-dione
  • 2-[(2R)-2-hydroxy-3-[[(1R,2S)-2-hydroxyindan-1-yl]amino]propyl]isoindoline-1,3-dione
  • 2-[(2R)-2-hydroxy-3-[[(1R)-1-(hydroxymethyl)-propyl]amino]propyl] isoindoline-1,3-dione
  • 2-[(2R)-2-hydroxy-3-[[(1S)-1-phenylethyl]-amino]propyl]isoindoline-1,3-dione
It may also be used in the synthesis of 2-((5R)-2-oxo-5-oxazolidinyl) methyl)-1H-isoindole-1,3 (2H)-dione.
Uses(R)-N-Glycidylphthalimide is a reagent used for the simultaneous preparation of amino alcohol solvating agents as well as preparation of orally available anticoagulants.
(R)-N-Glycidylphthalimide Preparation Products And Raw materials
(R)-5-chloro-N-(4-(3-oxomorpholino)phenyl)-N- ((2-oxooxazolidin-5-yl)methyl)thiophene-2-carboxamide 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- 2-Thiophenecarboxylic acid (S)-2-(3-chloro-2-hydroxypropyl)isoindoline-1,3-dione 5-CHLOROTHIOPHENE-2-CARBOXYLIC ACID Benzoic acid, 2-[[[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]aMino]carbonyl]- 3-Morpholinone, 4-(2,4-diaMinophenyl)- (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one.HCl 4-(4-NITROPHENYL)MORPHOLIN-3-ONE Rivaroxaban Impurity 93 4-(3-AMino-phenyl)-Morpholin-3-one 4-(2-nitrophenyl)Morpholin-3-one 4,5-DICHLOROTHIOPHENE-2-CARBOXYLIC ACID O-Phthalimide (S)-(+)-GLYCIDYL PHTHALIMIDE,(S)-GLYCIDYL PHTHALIMIDE Glycidyl phthalimide N-(2,3-EPOXYPROPYL)PHTHALIMIDE (R)-N-Glycidylphthalimide
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