4-Amino-6-chlorobenzene-1,3-disulfonamide

4-Amino-6-chlorobenzene-1,3-disulfonamide Basic information

Product Name:	4-Amino-6-chlorobenzene-1,3-disulfonamide
Synonyms:	4-amino-6-chloro-3-benzenedisulfonamide;5-Chloro-2,4-bis(sulfonamido)aniline;4-AMino-6-chloro-1,3-benzenedisulfonaMide 98%;Benzothiadiazine realted compound A;4-amino-6-chloro-1,3-benzenedisulphonamide;Hydrochlorothiazide EP Impurity B;LABOTEST-BB LT00261357;CHLORAMINOPHENAMIDE
CAS:	121-30-2
MF:	C6H8ClN3O4S2
MW:	285.73
EINECS:	204-463-1
Product Categories:	Phenyls & Phenyl-Het;Aromatics;Phenyls & Phenyl-Het;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;121-30-2
Mol File:	121-30-2.mol

4-Amino-6-chlorobenzene-1,3-disulfonamide Chemical Properties

Melting point	257-261 °C(lit.)
Boiling point	614.4±65.0 °C(Predicted)
density	1.584 (estimate)
refractive index	1.6100 (estimate)
storage temp.	2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
pka	9.24±0.60(Predicted)
form	Powder
color	White to off-white
Merck	14,2076
BRN	1083877
CAS DataBase Reference	121-30-2(CAS DataBase Reference)
EPA Substance Registry System	1,3-Benzenedisulfonamide, 4-amino-6-chloro- (121-30-2)

Safety Information

MSDS Information

Provider	Language
3-Chloro-4,6-disulfamoylaniline	English
SigmaAldrich	English

4-Amino-6-chlorobenzene-1,3-disulfonamide Usage And Synthesis

Chemical Properties	Light Brown Solid
Uses	Diuretic.
Uses	4-Amino-6-chloro-1,3-benzenedisulfonamide was used in the synthesis of deuterated thiazides by undergoing condensation with appropriately labeled aldehydes.
Definition	ChEBI: Chloraminophenamide is a sulfonamide.
General Description	Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

4-Amino-6-chlorobenzene-1,3-disulfonamide Preparation Products And Raw materials

Raw materials	3-Chloroaniline-->Chloramine-T-->4-AMINO-6-CHLORO-BENZENE-1,3-DISULFONYL DICHLORIDE-->Hydrochlorothiazide-->Hydrochlorothiazide Impurity 28-->Hydrochlorothiazide Impurity 4-->Trichlormethiazide
Preparation Products	Chlorothiazide-->4-AMINO-5,6-DICHLOROBENZENE-1,3-DISULFONAMIDE-->3-Des(allylthio)Methyl-3-chloroMethyl Althiazide-->EX5004

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