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| | Sodium danshensu Basic information |
| | Sodium danshensu Chemical Properties |
| storage temp. | Inert atmosphere,2-8°C | | solubility | H2O : 100 mg/mL (454.24 mM; Need ultrasonic)DMSO : 100 mg/mL (454.24 mM; Need ultrasonic) | | form | powder | | color | White-beige |
| Hazard Codes | Xn | | Risk Statements | 22 | | Safety Statements | 24/25 | | HS Code | 29329990 |
| | Sodium danshensu Usage And Synthesis |
| Description | Danshensu is a salvianolic acid and the major component of S. miltiorrhiza (Danshen) and has diverse biological activities. It reduces expression of the autophagy-associated proteins p62, LC3-II, and Beclin-1 and the apoptosis-related proteins Bax and caspase-3, prevents cardiomyocyte damage, and increases heart rate, coronary flow (CF), and left ventricular developed pressure (LVDP) in an isolated rat heart model of ischemia and reperfusion injury. Danshensu (60 mg/kg per day) reduces infarct size and improves left ventricular function in a rat model of myocardial infarction. It enhances radiation-induced tumor cell death in a Lewis lung carcinoma mouse xenograft model. Danshensu also decreases infarct volume, neuronal apoptosis, production of TNF-α, IL-1β, and IL-6, and superoxide dismutase (SOD) and glutathione peroxidase (GPx) activity in a rat model of cerebral ischemia and reperfusion injury. | | Chemical Properties | White to light brown powder | | Uses | Sodium Danshensu is exhibits protective effects on the excitotoxicity of monosodium glutamate in the late stage of pregnancy on developing mouse fetal brain. | | target | Calcium Channel | Potassium Channel | Akt | GSK-3 | Bcl-2/Bax | PI3K |
| | Sodium danshensu Preparation Products And Raw materials |
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