|
| | cephaeline hydrochloride Basic information |
| Product Name: | cephaeline hydrochloride | | Synonyms: | cephaelin hydrochloride;Cephaeline dihydrochloride;(1R)-1-[[(2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-6-isoquinolinol hydrochloride;NSC 32944;Cephaeline HCl salt;(-)-CEPHAELINE DIHYDROCHLORIDE;Cephaeline hydrochloride CRS;Cephaeline DiHCl | | CAS: | 5853-29-2 | | MF: | C28H39ClN2O4 | | MW: | 503.08 | | EINECS: | 227-463-3 | | Product Categories: | | | Mol File: | 5853-29-2.mol |  |
| | cephaeline hydrochloride Chemical Properties |
| storage temp. | 4°C, protect from light | | solubility | Soluble in DMSO | | form | neat |
| RIDADR | 1544 | | HazardClass | 6.1(b) | | PackingGroup | III | | Toxicity | LD50 oral in mouse: 74970ug/kg |
| | cephaeline hydrochloride Usage And Synthesis |
| Chemical Properties | Off-white to yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from ipecac, Angola anise maple. | | Uses | Epichenol hydrochloride can kill the trophozoites of lysosomes and is toxic. | | Biological Activity | Cephaeline dihydrochloride is a selective CYP2D6 inhibitor with IC50 of 121 μM. | | target | IC50: 121 μM (CYP2D6)
Ki: 54 μM (CYP2D6) |
| | cephaeline hydrochloride Preparation Products And Raw materials |
|
