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| | (1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic Acid Methyl Ester Basic information |
| Product Name: | (1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic Acid Methyl Ester | | Synonyms: | (1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic Acid Methyl Ester;(1S,3R)-1-(1;(1S,3R)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester;Tadalafil Impurity 8;Tadalafil impurity 10;Tadalafil-006;1H-Pyrido[3,4-b]indole-3-carboxylic acid,1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-, methylester, (1S,3R)-;Tadalafil-006-1S3R | | CAS: | 629652-40-0 | | MF: | C22H19ClN2O5 | | MW: | 426.85 | | EINECS: | | | Product Categories: | Aromatics;Heterocycles;Indole Derivatives;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 629652-40-0.mol | ![(1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic Acid Methyl Ester Structure](CAS/GIF/629652-40-0.gif) |
| | (1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic Acid Methyl Ester Chemical Properties |
| Melting point | 209 °C(Solv: ethyl ether (60-29-7)) | | Boiling point | 627.5±55.0 °C(Predicted) | | density | 1.445±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator, under inert atmosphere | | solubility | Chloroform (Slightly), DMSO (Slightly) | | form | Solid | | pka | 16.25±0.60(Predicted) | | color | Pale Yellow to Light Brown |
| | (1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic Acid Methyl Ester Usage And Synthesis |
| Uses | An intermediate in the preparation of cis-Tadalafil (T004520). A PDE5 inhibitor. |
| | (1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic Acid Methyl Ester Preparation Products And Raw materials |
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