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| | 2,4-Difluoronitrobenzene Basic information | | Synthesis |
| Product Name: | 2,4-Difluoronitrobenzene | | Synonyms: | 1,3-difluoro-4-nitrobenzene;1-Nitro-2,4-difluorobenzene;2,4-difluoro-1-nitro-benzen;2,4-Difluronitrobenzene;Benzene, 2,4-difluoro-1-nitro-;2,4-DIFLUORONITROBENZENE;2,4-DIFLUORO NITROBENZEN;2,4-Difluoronitribenzene | | CAS: | 446-35-5 | | MF: | C6H3F2NO2 | | MW: | 159.09 | | EINECS: | 207-167-0 | | Product Categories: | Fluorine series;alkyl Fluorine| nitro-compound;HALIDE;Aromatic Hydrocarbons (substituted) & Derivatives | | Mol File: | 446-35-5.mol |  |
| | 2,4-Difluoronitrobenzene Chemical Properties |
| Melting point | 9-10 °C (lit.) | | Boiling point | 203-204 °C (lit.) | | density | 1.451 g/mL at 25 °C (lit.) | | vapor density | >1 (vs air) | | refractive index | n20/D 1.511(lit.) | | Fp | 195 °F | | storage temp. | Sealed in dry,Room Temperature | | form | clear liquid | | color | Light yellow to Brown | | Specific Gravity | 1.45 | | Water Solubility | Insoluble in water. | | BRN | 2048034 | | Stability: | Stable. Incompatible with strong bases, strong oxidizing agents. Combustible. | | InChIKey | RJXOVESYJFXCGI-UHFFFAOYSA-N | | CAS DataBase Reference | 446-35-5(CAS DataBase Reference) | | NIST Chemistry Reference | 2,4-Difluoronitrobenzene(446-35-5) | | EPA Substance Registry System | 2,4-Difluoronitrobenzene (446-35-5) |
| | 2,4-Difluoronitrobenzene Usage And Synthesis |
| Synthesis | KF with n-Hexadecyltrimethylammonium bromide as the PTC has been shown
recently to work in dimethylformamide (DMF), important owing to the low cost16 of
DMF. | | Chemical Properties | yellow liquid | | Uses | 2,4-Difluoronitrobenzene has been used in the synthesis of 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction, (±)-horsfiline and resin-bound-2-arylaminobenzimidazoles. | | Uses | 2,4-Difluoronitrobenzene has been used in the synthesis of:
2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction;
(±)-horsfiline;
resin-bound 2-arylaminobenzimidazoles.
2,?4-?Difluoronitrobenzene is a reactant in the preparation of 4-?thiazolidinone derivatives as antimicrobial agents. | | Uses | 2,4-Difluoronitrobenzene has been used in the synthesis of:
- 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction
- (±)-horsfiline
- resin-bound 2-arylaminobenzimidazoles
| | General Description | Nucleophilic aromatic substitution of 2,4-difluoronitrobenzene with morpholine has been investigated using flow reactor with simulated moving bed (SMB) chromatography module. |
| | 2,4-Difluoronitrobenzene Preparation Products And Raw materials |
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