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| | SALVINORIN A Basic information |
| Product Name: | SALVINORIN A | | Synonyms: | Salvinorin A solution;[2S-(2α,4aα,6aβ,7β,9β,10aα,10bβ)]-9-(Acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-diMethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic Acid Methyl Ester;Salvinorin;2H-Naphtho[2,1-c]pyran-7-carboxylicacid, 9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-,methyl ester, (2S,4aR,6aR,7R,9S,10aS,10bR)-;SALVINORIN A(P);(2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(3-furanyl)dodechydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester;(2S,4aR,6aR,7R,9S,10aS,10bR)-9-(Acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester;Divinorin A | | CAS: | 83729-01-5 | | MF: | C23H28O8 | | MW: | 432.46 | | EINECS: | 689-027-2 | | Product Categories: | Neurochcemicals;Agonist;Opioids;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Opioid receptor and opioid-like receptor | | Mol File: | 83729-01-5.mol |  |
| | SALVINORIN A Chemical Properties |
| Melting point | 238-240° (Ortega); mp 242-244° (Valdes, 1984) | | alpha | D22 -45.3° (c = 8.530 in CHCl3); D25 -41° (c = 1 in CHCl3) | | Boiling point | 563.8±50.0 °C(Predicted) | | density | 1.28±0.1 g/cm3(Predicted) | | Fp | 2℃ | | storage temp. | −20°C | | solubility | DMSO: ≥10mg/mL | | form | powder | | color | white |
| | SALVINORIN A Usage And Synthesis |
| Description | Salvinorin A (Item No. 11487) is an analytical reference material categorized as a diterpene. It is a hallucinogen derived from S. divinorum that has been used in the traditional spiritual practices of the Mazatec Indians and as a recreational drug. This product is intended for research and forensic applications. | | Uses | Salvinorin A is a potent and selective kappa-opioid receptor agonist. Salvinorin A has been reported to be brain-penetrant and displays psychoactive properties; hallucinogen. | | Uses | Salvinorin A is a hallucinogenic derived from the S. divinorum plant used in traditional spiritual practices of the Mazatec Indians and now gaining popularity as a recreational drug. Unlike other hallucinogens, which mediate their effects through serotonin 5-HT2A receptors, salvinorin A is a potent, selective κ-opioid receptor agonist (Ki = 2.4 nM; EC50 = 1.8 nM). This product is intended for forensic and research applications.In traditional medicine, the leaves are used for divination and for treatment of anemia and excretory functions.
| | Uses | In traditional medicine, the leaves are used for divination and for treatment of anemia and excretory functions. | | Definition | ChEBI: A natural product found in Salvia divinorum. | | Biological Activity | Potent naturally occuring non-nitrogenous κ -opioid selective agonist that displays high affinity at both native (K i = 4.3 nM) and cloned (K i = 16 nM) κ -opioid receptors. Also exhibits allosteric modulation of μ -opioid receptor binding. Reported to be brain-penetrant and displays psychoactive properties. | | Biochem/physiol Actions | Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A displays high affinity at both native (Ki=4.3 nm) and cloned (Ki=16 nm) κ -opioid receptors. Preliminary studies suggest that Salvanorin A is chemically unique among the psychtropic drugs and does not bind to any known receptor. |
| | SALVINORIN A Preparation Products And Raw materials |
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