Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, mono[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethyl] ester

Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, mono[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethyl] ester Basic information
Product Name:Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, mono[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethyl] ester
Synonyms:Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, mono[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethyl] ester;Tenofovir Impurity 125
CAS:1878175-77-9
MF:C17H23N10O4P
MW:462.4
EINECS:
Product Categories:
Mol File:1878175-77-9.mol
Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, mono[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethyl] ester Structure
Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, mono[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethyl] ester Chemical Properties
Boiling point 790.9±70.0 °C(Predicted)
density 1.76±0.1 g/cm3(Predicted)
solubility DMSO (Slightly), Water (Slightly)
form Solid
pka2.27±0.10(Predicted)
color White to Off-White
Stability:Hygroscopic
Safety Information
MSDS Information
Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, mono[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethyl] ester Usage And Synthesis
Uses(R)-Bis(1-methylethyl) Ester [[2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid is a Tenofovir Disoproxil Fumarate (T018505) related compound which is an acyclic phosphonate nucleotide analogue
Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, mono[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethyl] ester Preparation Products And Raw materials
D-Alanine Isopropyl Ester HCl Tenofovir alafenamide fumarate isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Tenofovir Impurity 117 Tenofovir Related Compound 1 Tenofovir Related Compound 6 Diethyl phosphite (S)-propyl 2-aminopropanoate hydrochloride L-Alanine isopropyl ester hydrochloride Tenofovir Related Compound 4 Mono-POC Tenofovir Tenofovir Alafenamide Tenofovir Impurity 64 Adefovir Dipivoxil Impurity 24

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