METHYL 3,4-DIFLUOROBENZOATE

METHYL 3,4-DIFLUOROBENZOATE Basic information

Product Name:	METHYL 3,4-DIFLUOROBENZOATE
Synonyms:	RARECHEM AL BF 0215;Methyl 3,4-difluorobenzoate 97%;Methyl3,4-difluorobenzoate97%;2,4-DIFLUOROBENZOIC ACID METHYL ESTER;BUTTPARK 89\07-66;METHYL 3,4-DIFLUOROBENZENECARBOXYLATE;METHYL 3,4-DIFLUOROBENZOATE;METHYL 3,4-DIFLUOROB
CAS:	369-25-5
MF:	C8H6F2O2
MW:	172.13
EINECS:
Product Categories:	Acids & Esters;Fluorine Compounds;C8 to C9;Carbonyl Compounds;Esters;Aromatic Esters
Mol File:	369-25-5.mol

METHYL 3,4-DIFLUOROBENZOATE Chemical Properties

Melting point	23-27 °C (lit.)
Boiling point	88 °C
density	1.268±0.06 g/cm3(Predicted)
Fp	184 °F
storage temp.	Sealed in dry,Room Temperature
form	fused solid
color	White
CAS DataBase Reference	369-25-5(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	22-37/38-41
Safety Statements	26-36/39
WGK Germany	3
Hazard Note	Irritant
HS Code	2916310090

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

METHYL 3,4-DIFLUOROBENZOATE Usage And Synthesis

Chemical Properties	off-white powder
Uses	Methyl 3,4-Difluorobenzoate is used in preparation of disubstituted 1,5-Naphthyridines as ALK5 inhibitors and therapeutic uses thereof.

METHYL 3,4-DIFLUOROBENZOATE Preparation Products And Raw materials

Raw materials	3',4'-Difluoroacetophenone-->3,4-Difluorobenzoic acid-->3,4-Difluorobenzoyl chloride-->1,2-Difluorobenzene-->Methanol-->CARBON DIOXIDE-->tert-Butyl hydroperoxide-->3,4-Difluorobenzaldehyde-->3,4-Difluorobenzotrifluoride-->3,4-Dichlorobenzotrifluoride
Preparation Products	Methyl-4-amino-3-fluorobenzoate-->3,4-DIFLUOROBENZOIC ACID HYDRAZIDE-->Methyl 3-Fluoro-4-Morpholinobenzoate

ETHYL 3-METHOXY-2,4,5-TRIFLUOROBENZOATE 2,3,4,5-TETRAFLUORO-BENZOIC ACID METHYL ESTER RARECHEM AL BF 0314 (4,5-DICHLORO-6-OXO-1,6-DIHYDROPYRIDAZIN-1-YL)METHYL 2,6-DIFLUOROBENZOATE METHYL PENTAFLUOROBENZOATE METHYL 3,4,5-TRIFLUOROBENZENECARBOXYLATE ETHYL 2,3,4-TRIFLUOROBENZOATE 4,5-DIFLUOROPHTHALIC ANHYDRIDE RARECHEM AL BF 1232 ETHYL 2,4,5-TRIFLUORO-3-IODOBENZOATE 2 3 4 5 6-PENTAFLUOROBENZOIC ANHYDRIDE METHYL 2,3,4-TRIFLUOROBENZOATE AnthranceA 2',4',5',7'-TETRABROMO-4,5,6,7-TETRAFLUOROFLUORESCEIN DIACETATE ETHYL 2,4,5-TRIFLUOROBENZOATE {5-[3,5-di(trifluoromethyl)phenyl]-2-furyl}methyl 2,6-difluorobenzoate 3-HYDROXY-2,4,5-TRIFLUOROBENZOIC ACID ETHYL ESTER ETHYL 3,4-DIFLUOROBENZOATE

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