Propanoic acid, 2-?hydroxy-?, polymer with 2-?hydroxyacetic acid

Propanoic acid, 2-?hydroxy-?, polymer with 2-?hydroxyacetic acid Basic information
Description Uses
Product Name:Propanoic acid, 2-?hydroxy-?, polymer with 2-?hydroxyacetic acid
Synonyms:PURASORB(R) PD;PURASORB(R) PDL;POLY(DL-LACTIDE);POLY(D-LACTIDE);D-LACTIDE POLYMER;LACTEL BP-0500;POLYGLYCOLIDE M.W. 100 000-125 000;POLY(DL-LACTIDE) M.W. 90,000-120,000
CAS:34346-01-5
MF:C5H10O6
MW:166.13
EINECS:
Product Categories:PLGA
Mol File:34346-01-5.mol
Propanoic acid, 2-?hydroxy-?, polymer with 2-?hydroxyacetic acid Structure
Propanoic acid, 2-?hydroxy-?, polymer with 2-?hydroxyacetic acid Chemical Properties
Melting point 262 °C(lit.)
density 1.53 g/mL at 25 °C(lit.)
storage temp. 2-8°C
solubility DMSO : 100 mg/mL ;chloroform : 16.67 mg/mL ;Water : < 0.1 mg/mL (insoluble)
Safety Information
WGK Germany 3
10-21
MSDS Information
ProviderLanguage
SigmaAldrich English
Propanoic acid, 2-?hydroxy-?, polymer with 2-?hydroxyacetic acid Usage And Synthesis
Description

Poly(D-lactide) (PDLA), a polymer of a stereospecific cyclic di-ester of lactic acid, is used in biomaterial research for the development of devices such as therapeutic drug delivery vessels. Poly(D-lactide) is used for the preparation of microparticles and resorbable polylactide scaffolds.
By poly (D-lactide) made products biological compatibility is good, after the in vivo degradation product by the metabolism out of the body, no harmful and toxic side effects on the human body.

Uses

Poly D-lactide is a bioabsorbable and degradable material. Poly D-lactide can be used in medical fields, such as disposable infusion devices, non-removable surgical sutures; controlled release and slow release packaging agents; tissue engineering scaffolds, bone fixation and bone repair materials, microcapsules for injection, microspheres, implant And animal organs support elastomers and other materials.
At present, it is widely used in the fields of medicine, such as disposable infusion apparatus, free disassembly type suture; drug controlled release, sustained release agent packaging; scaffolds for tissue engineering, bone fixation and bone repairing material, injection with of microcapsules and microspheres, implants and animal organs elastomer material support.

UsesUsed in Drug Delivery including coating nanoparticles. Can be end-group functionalizated or used as a macroinitiator/block precursor.
UsesSurgical aid (surgical suture material, absorbable).
Brand nameVicryl (Ethicon).
Propanoic acid, 2-?hydroxy-?, polymer with 2-?hydroxyacetic acid Preparation Products And Raw materials
Lpla:(Poly(L-Lactide) POLY(DL-LACTIDE-CO-CAPROLACTONE) (86:14),POLY(DL-LACTIDE-CO-CAPROLACTONE) (86:14) Plga:(Poly(Dl-Lactide-Co-Glycolide),Plga:(Poly(Dl-Lactide-Co-Glycolide) Dlpla:(Poly(Dl-Lactide),Dlpla:(Poly(Dl-Lactide) poly(ethyleneglycol-lactide) Tris(2,4-pentanedionato)chroMiuM(III) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) POLY(L-LACTIDE-CO-CAPROLACTONE-CO-GLYCOLIDE) 2,4-PENTANEDIONE, SILVER DERIVATIVE POLY(DL-LACTIDE-CO-CAPROLACTONE),POLY(DL-LACTIDE-CO-CAPROLACTONE) POLY(L-LACTIDE)RESINS COBALT(II) ACETYLACETONATE Cupric acetylacetonate Ferric acetylacetonate COBALT ETHYLENE DIAMINE CHLORIDE POLY(L-LACTIDE),poly(L-lactide) M.W. 85,000-160,000 POLY(L-LACTIDE-CO-CAPROLACTONE-CO-GLYCO& POLY(DL-LACTIDE), INHERENT VISCOSITY 0.5,POLY(DL-LACTIDE) INHERENT VISCOSITY,POLY(DL-LACTIDE) INHERENT VISCOSITY,POLY(DL-LACTIDE), INHERENT VISCOSITY 0.5

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