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| | (+/-)-alpha-Lipoamide Basic information |
| Product Name: | (+/-)-alpha-Lipoamide | | Synonyms: | DL-ALPHA-LIPOAMIDE;DL-6,8-THIOCTIC ACID AMIDE OXIDIZED FORM;DL-6,8-EPIDITHIOOCTANAMIDE;DL-6,8-THIOCTAMIDE;DL-6,8-THIOCTIC ACID AMIDE;DL-THIOCTAMIDE;DL-LIPOAMIDE OXIDIZED FORM;6-THIOCTIC AMIDE | | CAS: | 940-69-2 | | MF: | C8H15NOS2 | | MW: | 205.34 | | EINECS: | 213-375-2 | | Product Categories: | Heterocyclic Compounds | | Mol File: | 940-69-2.mol |  |
| | (+/-)-alpha-Lipoamide Chemical Properties |
| Melting point | 127-129 °C(lit.) | | Boiling point | 399.2±11.0 °C(Predicted) | | density | 1.1989 (rough estimate) | | refractive index | 1.5364 (estimate) | | storage temp. | Sealed in dry,2-8°C | | solubility | Dichloromethane (Slightly), DMSO (Slightly, Heated, Sonicated), Ethanol (Slightly) | | pka | 16.59±0.40(Predicted) | | form | Solid | | color | Pale Yellow to Yellow | | CAS DataBase Reference | 940-69-2(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 22 | | Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | JP1185000 |
| | (+/-)-alpha-Lipoamide Usage And Synthesis |
| Uses | (±)-α-Lipoamide may be used in treatment of insulin resistance by stimulating mitochondrial biogenesis. When used in combination with Alprostadil, it has shown to have a good therapeutic effect on early diabetic nephropathy. | | Definition | ChEBI: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of lipoic acid with ammonia. | | storage | Store at -20°C | | Purification Methods | DL--Lipoamide is recrystallised from EtOH and has UV with max 331nm in MeOH. [Reed et al. J Biol Chem 232 143 1958, IR: Wagner et al. J Am Chem Soc 78 5079 1956, Beilstein 19/7 V 238.] |
| | (+/-)-alpha-Lipoamide Preparation Products And Raw materials |
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