ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards XXZJUZXKBFUPQH-IKGGRYGDSA-N

XXZJUZXKBFUPQH-IKGGRYGDSA-N

XXZJUZXKBFUPQH-IKGGRYGDSA-N Basic information
Product Name:XXZJUZXKBFUPQH-IKGGRYGDSA-N
Synonyms:XXZJUZXKBFUPQH-IKGGRYGDSA-N;(2R,?3R,?6S)?-6-?(4-?Fluorophenyl)?tetrahydro-?2-?(4-?hydroxyphenyl)?-2H-pyran-3-carboxylic Acid;(2R,3R,6S)-6-(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H- pyran-3-carboxylic acid;Ezetimibe Impurity 116;2H-Pyran-3-carboxylic acid, 6-(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-, (2R,3R,6S)-;Ergosterol Impurity 1
CAS:1618657-31-0
MF:C18H17FO4
MW:316.32
EINECS:
Product Categories:
Mol File:1618657-31-0.mol
XXZJUZXKBFUPQH-IKGGRYGDSA-N Structure
XXZJUZXKBFUPQH-IKGGRYGDSA-N Chemical Properties
Boiling point 528.8±50.0 °C(Predicted)
density 1.313±0.06 g/cm3(Predicted)
solubility Chloroform, DCM
form Solid
pka4.17±0.60(Predicted)
color White
Safety Information
MSDS Information
XXZJUZXKBFUPQH-IKGGRYGDSA-N Usage And Synthesis
Uses(2R,?3R,?6S)?-6-?(4-?Fluorophenyl)?tetrahydro-?2-?(4-?hydroxyphenyl)?-2H-pyran-3-carboxylic Acid is an impurity of Ezetimibe (E975000), a drug that lowers plasma cholesterol levels.
XXZJUZXKBFUPQH-IKGGRYGDSA-N Preparation Products And Raw materials
ent-EzetiMibe EzetiMibe (3R,4R,3'S)-IsoMer (R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one (3R,4R)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one 4a€-O-Benzyloxy (3S,4S)-Ezetimibe (4S)-3-(2,2-dimethylpropanoyl)-4-phenyl-1,3-oxazolidin-2-one 4-BENZOYLBUTYRIC ACID (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole 2-Oxazolidinone, 3-[(2R,5S)-5-(4-fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-, (4S)-rel- 2-{[(4-fluorophenyl)imino]methyl}phenol (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one EzetiMibe ring-opening dehydrate iMpurity 3-O-Acetyl Ezetimibe ent-Ezetimibe Ketone Ezetimibe Impurity 82 Ezetimibe Impurity 36 Ezetimibe Impurity 79 (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone
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