5-Amino-2-methoxypyridine

5-Amino-2-methoxypyridine Basic information

Product Name:	5-Amino-2-methoxypyridine
Synonyms:	3-PYRIDINAMINE, 6-METHOXY-;5-AMINO-2-METHOXYPYRIDINE;6-Methoxy-3-pyridylamine;6-METHOXY-PYRIDIN-3-YLAMINE;2-METHOXY-5-AMINOPYRIDINE;OTAVA-BB BB7020410079;3-Amino-6-methoxypyridine;5-amino-2-methoxy-pyridin
CAS:	6628-77-9
MF:	C6H8N2O
MW:	124.14
EINECS:	229-612-8
Product Categories:	Amino-pyridine series;Pyridines derivates;Pyridines;Boronic Acid;C6;Heterocyclic Building Blocks;Pyridine;Pyridines, Pyrimidines, Purines and Pteredines;Pyridine series;piridines
Mol File:	6628-77-9.mol

5-Amino-2-methoxypyridine Chemical Properties

Melting point	29-31 °C (lit.)
Boiling point	85-90 °C/1 mmHg (lit.)
density	1.575
refractive index	n20/D 1.575(lit.)
Fp	>230 °F
storage temp.	2-8°C
solubility	Chloroform, Methanol (Slightly)
form	Liquid
pka	4.33±0.10(Predicted)
color	Yellow-brown or red to very dark red
Water Solubility	Slightly soluble
CAS DataBase Reference	6628-77-9(CAS DataBase Reference)
NIST Chemistry Reference	5-Amino-2-methoxypyridine(6628-77-9)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	22-36/37/38
Safety Statements	26-37/39-36
WGK Germany	3
RTECS	US1836000
HazardClass	IRRITANT
HS Code	29339900

MSDS Information

Provider	Language
6-Methoxy-3-pyridylamine	English
SigmaAldrich	English
ACROS	English

5-Amino-2-methoxypyridine Usage And Synthesis

Chemical Properties	yellow-brown or red to very dark red liquid
Uses	5-Amino-2-methoxypyridine is used as a reagent in the synthesis of a novel series of thienopyrimidines as highly potent and selective PI3K inhibitors. 5-Amino-2-methoxypyridine is also used to synthesize EMPA (E521550); a novel high-affinity selective antagonist for the OX2 receptor.
Definition	ChEBI: 6-Methoxypyridin-3-amine is an aminopyridine.

5-Amino-2-methoxypyridine Preparation Products And Raw materials

Raw materials	Ethanol-->Methanol-->Sodium hydride-->Iron-->Sodium sulfite-->Sodium dithionite-->2-Chloro-5-nitropyridine-->2-Methoxy-5-nitropyridine
Preparation Products	5-AMINO-2-METHOXY-ISONICOTINIC ACID-->3-AMINO-2-BROMO-6-METHOXYPYRIDINE-->5-FLUORO-2-METHOXYPYRIDINE-4-BORONIC ACID-->5-Hydrazinyl-2-Methoxypyridine hydrochloride-->2-BROMO-5-FLUORO-3-NITROPYRIDINE-->5-HYDRAZINO-2-METHOXYPYRIDINE-->1-(6-METHOXYPYRIDIN-3-YL)PIPERAZINE-->1H-Pyrrolo[2,3-c]pyridine-7-carboxaldehyde,4-fluoro-(9CI)-->2-hydrazino-N-(6-methoxypyridin-3-yl)-2-oxoacetamide

2-Amino-5-methoxypyridine 5-(TERT-BUTOXYCARBONYLAMINO)-2-METHOXYPYRIDINE-4-CARBOXYLIC ACID 2-Methoxypyridine ALTRENOGEST Anisole 3-Aminopyridine (Trifluoromethoxy)benzene Glycine 3-amino-6-methoxypyridine-2-thiol 5-Bromo-2-methoxypyridine 2-Aminopyridine Tris(hydroxymethyl)aminomethane 2-Methoxy-5-nitropyridine 2-METHOXY-4-AMINOPYRIDINE,4-Amino-6-methoxypyridine,4-AMINO-2-METHOXYPYRIDINE AMINO ACIDS 2-Methoxy-5-fluoropyridine 5-Amino-2-methoxypyridine 4-Dimethylaminopyridine

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