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Irinotecan Hydroxyl Acid

Irinotecan Hydroxyl Acid Basic information
Product Name:Irinotecan Hydroxyl Acid
Synonyms:Irinotecan Hydroxyl Acid;Irinotecan IMpurity;Irinotecan Impurity 28;Indolizino[1,2-b]quinoline-7-acetic acid, α,12-diethyl-9,11-dihydro-α,2-dihydroxy-8-(hydroxymethyl)-9-oxo-, (αS)-
CAS:142677-15-4
MF:C22H22N2O6
MW:410.43
EINECS:
Product Categories:
Mol File:142677-15-4.mol
Irinotecan Hydroxyl Acid Structure
Irinotecan Hydroxyl Acid Chemical Properties
Boiling point 829.8±65.0 °C(Predicted)
density 1.54±0.1 g/cm3(Predicted)
solubility DMSO (Slightly, Heated), Methanol (Slightly, Sonicated), Water (Slightly)
form Solid
pka2.88±0.10(Predicted)
color Light Yellow to Dark Yellow
Stability:Hygroscopic
Safety Information
MSDS Information
Irinotecan Hydroxyl Acid Usage And Synthesis
UsesThe active metabolite of Irinotecan (carboxylate form). SN-38 lactone and carboxylate may be considered pharmacokinetically distinct agents.
Irinotecan Hydroxyl Acid Preparation Products And Raw materials
sodium:(2S)-2-[12-ethyl-8-(hydroxymethyl)-9-oxo-2-(4-piperidin-1-ylpiperidine-1-carbonyl)oxy-11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoate Irinotecan Impurity 24 7,11-Diethyl-10-hydroxycaMptothecin 1-benzyl-4-(piperidin-1-yl)-1,2,3,6-tetrahydropyridine Irinotecan Impurity 6 Irinotecan EP Impurity H 12-Hydroxy Irinotecan 1-CHLOROCARBONYL-4-PIPERIDINOPIPERIDINE 10-Hydroxycamptothecin Irinotecan Impurity 29 Irinotecan Impurity 8 1-Piperidinecarbonyl chloride, 4-oxo- (9CI) 12-ethyl-8-methyl-9-oxo-7-propionyl-9,11-dihydroindolizino[1,2-b]quinolin-2-yl [1,4'-bipiperidine]-1'-carboxylate Irinotecan Impurity 3 Irinotecan Impurity 26 4-Piperidinone Irinotecan Impurity 19 Irinotecan Lactone IMpurity
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