4-[-((-((4-(5-(Bis(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoyl)oxy)ethyl)(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanic Acid

4-[-((-((4-(5-(Bis(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoyl)oxy)ethyl)(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanic Acid Basic information
Product Name:4-[-((-((4-(5-(Bis(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoyl)oxy)ethyl)(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanic Acid
Synonyms:4-[-((-((4-(5-(Bis(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoyl)oxy)ethyl)(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanic Acid;BendaMustine DiMer IMpurity;BendaMustine DiMer IMpurity Dihydrochloride;BendaMustine DiMer IMpurity Replaces B132525;Bendamustine USP RC H;Bendamustine Impurity I;4-[5-[2-[4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoyloxy]ethyl-(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid;Bendamustine USP RC H( Trichloroethyl Dimer,
CAS:1228551-91-4
MF:C32H41Cl3N6O4
MW:680.06
EINECS:
Product Categories:Amines;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:1228551-91-4.mol
4-[-((-((4-(5-(Bis(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoyl)oxy)ethyl)(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanic Acid Structure
4-[-((-((4-(5-(Bis(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoyl)oxy)ethyl)(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanic Acid Chemical Properties
Melting point >45°C (dec.)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
color Off-White to Dark Orange
Stability:Moisture Sensitive
Safety Information
HS Code 2933998350
MSDS Information
4-[-((-((4-(5-(Bis(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoyl)oxy)ethyl)(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanic Acid Usage And Synthesis
UsesBendamustine Dimer is an impurity of Bendamustine (B132500), an anticancer drug.
4-[-((-((4-(5-(Bis(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoyl)oxy)ethyl)(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanic Acid Preparation Products And Raw materials
5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester Bendamustine Montelukast Bis-sulfide (Mixture of Diastereomers) Bendamustine Ether Impurity Montelukast Sulfone 3S, 5S enantioMer of Atorvastatin CalciuM Montelukast EP IMpurity E Atorvastatin Epoxy Tetrahydrofuran IMpurity DesMethyl BendaMustine Hydrochloride 5-[Bis(2-chloroethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Methyl Ester Bendamustine Impurity 8 Bendamustine D-Mannitol Ester 5-[Bis(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Atorvastatin Ethyl Ester BendaMustine IMpurity C   N1-Methylbenzene-1,2,4-triaMine Bendamustine Impurity 16 GLUTARIC ACID-2-METHYLAMINO-5-NITROMONOANILIDE

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