10-trans-Atorvastatin Acetonide tert-Butyl Ester

10-trans-Atorvastatin Acetonide tert-Butyl Ester Basic information
Product Name:10-trans-Atorvastatin Acetonide tert-Butyl Ester
Synonyms:(3S,5R)-Atorvastatin Acetonide tert-Butyl Ester;Atorvastatin Acetonide t-Butyl Ester (4S, 6R)-Isomer;10-trans-Atorvastatin Acetonide tert-Butyl Ester;(4S,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-Methylethyl)-3-phenyl-4-[(phenylaMino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester;tert-butyl 2-((4S,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl -4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan -4-yl)acetate;tert-butyl 2-[(4S,6R)-6-[2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate;Atorvastatin impurity 25/10-trans-Atorvastatin Acetonide tert-Butyl Ester/(4S,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester;Atorvastatin calcium-26
CAS:1105067-90-0
MF:C40H47FN2O5
MW:654.81
EINECS:
Product Categories:Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:1105067-90-0.mol
10-trans-Atorvastatin Acetonide tert-Butyl Ester Structure
10-trans-Atorvastatin Acetonide tert-Butyl Ester Chemical Properties
Melting point 142-143°C
Boiling point 678.0±55.0 °C(Predicted)
density 1.14±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility Dichloromethane
pka13.57±0.70(Predicted)
form Solid
color Off-White
Safety Information
MSDS Information
10-trans-Atorvastatin Acetonide tert-Butyl Ester Usage And Synthesis
Chemical PropertiesOff-White Solid
UsesIntermediate in the preparation of Atorvastatin 10-Trans (Atorvastatin Impurity AT10)
Atorvastatin Oxirane Impurity 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt Atorvastatin IMpurity G Atorvastatin Impurity 20 2,3-Dehydroxy Atorvastatin Sodium Salt 2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide Atorvastatin Impurity 15 Atorvastatin Dihydroxy Diketo Atorvastatin IMpurity Ortho-Hydroxy atorvastatin calcium salt O-Methyl Atorvastatin Calcium Salt Atorvastatin Dehydro Lactone Difluoro Atorvastatin Acetonide tert-Butyl Ester Atorvastatin Impurity 31 3-Oxo Atorvastatin tert-Butyl Ester Atorvastatin Impurity 38 Atorvastatin Impurity 46 5-Oxo Atorvastatin tert-Butyl Ester

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