|
| | O-Benzyl Posaconazole Basic information |
| Product Name: | O-Benzyl Posaconazole | | Synonyms: | O-Benzyl Posaconazole;2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-(phenylMethoxy)propyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]Methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol;D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-(phenylMethoxy)propyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]Methyl]-1-(1H-1,2,4-triazol-1-yl)-;O-Benzyl Posaconazole
4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-(benzyloxy)pentan-3-yl)-1H-1,2,4-triazol-5(4H)-one;Posaconazole O-Benzyl Impurity;Posaconazole Impurity 68(Posaconazole O-Benzyl Impurity);4-(4-(4-(4-(((3R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)-tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3S)-2-(benzyloxy)pentan-3-yl)-2H-1,2,4-triazol-3(4H)-one CAS NO : 170985-86-1;Benzylated Posaconazole Impurity | | CAS: | 170985-86-1 | | MF: | C44H48F2N8O4 | | MW: | 790.9 | | EINECS: | | | Product Categories: | Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 170985-86-1.mol |  |
| | O-Benzyl Posaconazole Chemical Properties |
| Boiling point | 889.9±75.0 °C(Predicted) | | density | 1.30±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | pka | 6.49±0.40(Predicted) | | color | Pale Beige |
| | O-Benzyl Posaconazole Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Uses | Precursor to the fungicide, Posaconazole. |
| | O-Benzyl Posaconazole Preparation Products And Raw materials |
| Raw materials | 454479-39-1-->1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine-->2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one,-->(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester-->454479-36-8-->Toluene-4-sulfonic acid 5-(2,4-difluoro-phenyl)-5-[1,2,4]triazol-1-ylMethyl-tetrahydro-furan-3-ylMethyl-->D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)--->Posaconazole Impurity 33-->2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde-->4-Bromophenol | | Preparation Products | Posaconazole |
|
