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Iopromide

Iopromide Basic information
Product Name:Iopromide
Synonyms:1,3-benzenedicarboxamide,n,n’-bis(2,3-dihydroxypropyl)-5-((methoxyacetyl)amino;6-triiodo-)-n-methyl-4;shl414c;IOPROMIDE;N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-N'-methylbenzene-1,3-dicarboxamide;Iopromide（mixture of isomers）;Iopromid;oproMide
CAS:73334-07-3
MF:C18H24I3N3O8
MW:791.11
EINECS:277-385-9
Product Categories:Isotope Labelled Compounds;Amines;Aromatics;Diagnostic;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:73334-07-3.mol
Iopromide Structure
Iopromide Chemical Properties
Melting point broad (160?C transition)
Boiling point 840.9±65.0 °C(Predicted)
density 2.173±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility Freely soluble in water and in dimethyl sulfoxide, practically insoluble in ethanol (96 per cent) and in acetone.
pka10.62±0.70(Predicted)
form neat
Stability:Hygroscopic
CAS DataBase Reference73334-07-3(CAS DataBase Reference)
EPA Substance Registry System1,3-Benzenedicarboxamide, N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-N1-methyl- (73334-07-3)
Safety Information
Hazard Codes N
Risk Statements 50/53
Safety Statements 60-61
RIDADR UN 3077 9 / PGIII
WGK Germany 3
RTECS CZ2230000
HS Code 2924296000
ToxicityLD50 in mice, rats (g iodine/kg body weight): 16.5, 11.4 i.v. (Muetzel)
MSDS Information
Iopromide Usage And Synthesis
DescriptionIopromide is a non-ionic, water-soluble X-ray contrast agent for intravascular administration. Iopromide can cause acute kidney injury and is used in animal models of contrast-induced nephropathy.
Chemical PropertiesWhite Solid
UsesContrast molecule
UsesLabelled Iopromide. Nonionic, injectable radio-contrast medium. Diagnostic aid (radiopaque medium).
DefinitionChEBI: A dicarboxylic acid diamide that consists of N-methylisophthalamide bearing three iodo substituents at positions 2, 4 and 6, a methoxyacetyl substituent at position 5 and two 2,3-dihydroxypropyl groups attached to the amide nitrogens. A ater soluble x-ray contrast agent for intravascular administration.
Brand nameUltravist (Berlex).
General DescriptionIopromide is a low-osmolar,nonionic monomer with 48% bound iodine content. It is indicatedfor use in angiography, excretory urography, andnumerous CT procedures.
Side effectsMost common adverse reactions (>1%) are headache, nausea, injection site and infusion site reactions, vasodilatation, vomiting, back pain, urinary urgency, chest pain, pain, dysgeusia, and abnormal vision.
5-AMINO-ISOPHTHALAMIDE 5-Amino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide 3,5-DIMETHYL-4-IODOANILINE 2-anilinoethanol hydroiodide IOPROMIDE RELATED COMPOUND A (50 MG) (5-AMINO-N,N'-BIS(2,3-DIHYDROXYPROPYL)-2,4,6-TRIIO-DO-N-METHYL-1,3-BENZENEDICARBOXAMIDE) 3-DIMETHYLAMINOMETHYL-BENZYLAMINE 5-Amino-N,N'-bis(2,3-dihydroxypropyl)isophthalamide 2,4-DIIODO-3,5-DIMETHYLANILINE 5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide 1,3-DIIODO-2,4-DIMETHYLBENZENE 3,5-DIMETHYL-4-IODO-ACETANILIDE Iodine 4-Iodo-N,N-dimethylbenzamide 3-AMINOMETHYL-N,N-DIMETHYL-BENZAMIDE 3-(N-BENZYL-N-METHYLAMINO)-1,2-PROPANEDIOL IOPROMIDE RELATED COMPOUND A (50 MG) (5- AMINO-N,N'-BIS(2,3-DIHYDROXYPROPYL)-2,4,6-TRIIO- DO-N-METHYL-1,3-BENZENEDICARBOXAMIDE) Iopromide Formamide
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