4-N-BOC-Aminopiperidine

4-N-BOC-Aminopiperidine Basic information
Description
Product Name:4-N-BOC-Aminopiperidine
Synonyms:4-(TERT-BUTOXYCARBONYLAMINO)PIPERIDINE;4-N-TERT-BOC-AMINO PIPERIDINE;4-N-(TERT-BUTOXYCARBONYL)AMINOPIPERIDINE;4-BOC-AMINOPIPERIDINE;4-AMINOPIPERIDINE, 4-BOC PROTECTED;4-(N-BOC-AMINO)PIPERIDINE;4-(tert-ButoxycarbonylaMino)piperidine, 98.0%(GC&T;CARBAMIC ACID, 4-PIPERIDINYL-, 1,1-DIMETHYLETHYL ESTER
CAS:73874-95-0
MF:C10H20N2O2
MW:200.28
EINECS:616-026-6
Product Categories:Pyrans, Piperidines & Piperazines;Building Blocks;Pyridine series;Pyrans, Piperidines &Piperazines;Piperidines;Heterocyclic Building Blocks;Amines;blocks;pharmacetical;Piperidine;73874-95-0
Mol File:73874-95-0.mol
4-N-BOC-Aminopiperidine Structure
4-N-BOC-Aminopiperidine Chemical Properties
Melting point 162-166 °C(lit.)
Boiling point 80°C/0.05mm
density 1.02±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Methanol
pka12.39±0.20(Predicted)
form Crystalline Powder
color Off-white
Sensitive Air Sensitive
InChIInChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-8-4-6-11-7-5-8/h8,11H,4-7H2,1-3H3,(H,12,13)
InChIKeyCKXZPVPIDOJLLM-UHFFFAOYSA-N
SMILESC(OC(C)(C)C)(=O)NC1CCNCC1
CAS DataBase Reference73874-95-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
HazardClass IRRITANT
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
4-N-BOC-Aminopiperidine Usage And Synthesis
Description4-(N-Boc-amino)piperidone may be used as a functionalization reagent for introduction of a primary and a tertiary amino group to poly(2-isopropyl-2-oxazoline. It can also be used as pharma building block. It is used in the synthesis of a piperidine-4-carboxamide CCR5 antagonist with potent anti-HIV 1-activity. It is an intermediate for the synthesis of various pharmaceutical and biologically active compounds, including inhibitors and therapeutic agents. It is used for the synthesis of diphenyl purine derivatives as peripherally selective cannabinoid receptor 1 Antagonists.
Chemical Propertiesoff-white crystalline powder
UsesPharma building block.
General Description4-(N-Boc-amino)piperidone is a piperidone derivative.
tert-butyl 4-amino-1-piperidinecarboxylate hydrochloride (4-BOC-AMINO-PIPERIDIN-1-YL)-NAPHTHALEN-2-YL-ACETIC ACID 1-N-(3'-INDOLE)ETHYL-4-BOC-AMINOPIPERIDINE 4-N-Boc-4-N-Methyl-aminopiperidine L-TRANSHOMOPRO(4-NHBOC)-OME 4-BOC-AMINO-1-[1-(4-FLUORO-BENZYL)-1H-BENZOIMIDAZOL-2-YL]-PIPERIDINE 4-AMINO-1-BOC-PIPERIDINE-4-CARBOXYLIC ACID 1-BENZYL-4-(N-BOC-AMINO) PIPERIDINE 98 4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-TERT-BUTYL ESTER (4-BOC-AMINO-PIPERIDIN-1-YL)-PYRIDIN-4-YL-ACETIC ACID (4-BOC-AMINO-PIPERIDIN-1-YL)-THIOPHEN-2-YL-ACETIC ACID BUTTPARK 52\08-74 (4-BOC-AMINO-PIPERIDIN-1-YL)-(1H-INDOL-2-YL)-ACETIC ACID FMOC-L-TRANSHOMOPRO(4-NHBOC) 4-(Boc-amino)-1-(Fmoc-piperidinyl)-4-carboxylic Acid 4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONOBENZYL ESTER 4-N-BOC-Aminopiperidine DI-TERT-BUTYL ETHER

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