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| | POLYETHYLENEIMINE Chemical Properties |
| Melting point | 59-60°C | | Boiling point | 250 °C(lit.) | | density | 1.030 g/mL at 25 °C | | vapor pressure | 9 mmHg ( 20 °C) | | refractive index | n20/D 1.5290 | | Fp | >230 °F | | storage temp. | 2-8°C | | solubility | DMSO (Sparingly) | | form | Liquid | | Specific Gravity | 1.045 (20/4℃) | | color | Pale yellow | | PH | pH(50g/l, 25℃) : 10～12 | | Water Solubility | Soluble in water. | | Sensitive | Hygroscopic | | InChI | InChI=1S/C2H5N/c1-2-3-1/h3H,1-2H2 | | InChIKey | NOWKCMXCCJGMRR-UHFFFAOYSA-N | | SMILES | C1NC1 | | LogP | -0.969 (est) | | EPA Substance Registry System | Aziridine, homopolymer (9002-98-6) |
| Provider | Language |
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ALFA
| English |
| | POLYETHYLENEIMINE Usage And Synthesis |
| Description | Polyethyleneimine (PEI), an organic polyamine polymer, is one of the
most prominent examples of cationic polymers capable of gene
transfection in vitro and in vivo into various cell lines and
tissues. PEI was also applied in different fields from gene therapy
and several studies have emphasized the importance of this polymer in
medicinal chemistry. | | Chemical Properties | Clear viscous liquid | | Uses | Polyethyleneimine is used as a polyelectrolyte multilayer on charged surfaces to provide a biocompatible coating on surfaces.1Detergents, adhesives, water treatment, printing inks, dyes, cosmetics, and paper industry, adhesion promoter, lamination primer, fixative agent, flocculant, cationic dispersant, stability enhancer, surface activator, chelating agent, scavenger for aldehydes and oxides.
| | Uses | Polyethyleneimine acts as a protein precipitant used to purify proteins. It is used as a chelating agent and as a scavenger for aldehydes and oxides. It is also used in detergents, paper industry, dyes, printing inks and in water treatment. | | Uses | Branched polyethyleneimine (PEI) is widely used in many applications due to its polycationic character. Unlike its linear equivalent, branched PEI contains primary, secondary, and tertiary amines. Primarily utilized in industrial applications, high molecular weight PEI has been used as a flocculating agent, textile coating, adhesion promoter, enzyme carrier, and as a material for CO2 capture. | | Definition | ChEBI: Aziridine is a saturated organic heteromonocyclic parent, a member of aziridines and an azacycloalkane. It has a role as an alkylating agent. It is a conjugate base of an aziridinium. | | General Description | All polyethylene imine polymers are hydrophilic and may contain approx. 30% hydrated water. | | Biological Activity |
Polyethylenimine is nondegradable and the molecular weight of PEI affects the cytotoxicity and gene transfer activity. Polyethylenimine acts as a low toxicity and efficient gene vector.
| | Structure and conformation | Polyethyleneimine(PEI) exists as both a branched and linear structure. Branched PEI (bPEI) is synthesized via acid-catalyzed polymerization of aziridine, whereas the linear structure (lPEI) is synthesized via ring opening polymerization of 2-ethyl-2-oxazoline followed by hydrolysis.
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| | POLYETHYLENEIMINE Preparation Products And Raw materials |
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