|
| | Sodium levothyroxine Basic information | | Uses |
| Product Name: | Sodium levothyroxine | | Synonyms: | SODIUM LEVOTHYROXINE;SODIUM LEVOTHYROXINE, HYDRATE;sodium (2s)-2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]propanoate;3-[4-4-HYDROXY-3,5-DIIODOPHENOXY-3,5-DIIODOPHENYL]-L-ALANINE, HYDRATE;L-THYROXINE SODIUM SALT;L-THYROXINE SODIUM SALT, HYDRATE;L-THYROXINE SODIUM, HYDRATE;L-THYROXIN SODIUM | | CAS: | 25416-65-3 | | MF: | C15H10I4NNaO4 | | MW: | 798.85 | | EINECS: | 685-634-1 | | Product Categories: | Hormone Drugs;25416-65-3 | | Mol File: | 25416-65-3.mol |  |
| | Sodium levothyroxine Chemical Properties |
| Melting point | 207 °C | | alpha | 16 º (c=2,1M HCl/alcohol 1/4) | | storage temp. | Inert atmosphere,2-8°C | | solubility | Very slightly soluble in water, slightly soluble in ethanol (96 per cent). It dissolves in dilute solutions of alkali hydroxides. | | form | Liquid | | color | Clear yellow to yellow-greenish | | Water Solubility | 0.15 g/L (25 ºC) | | Stability: | Hygroscopic | | CAS DataBase Reference | 25416-65-3(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29379000 |
| | Sodium levothyroxine Usage And Synthesis |
| Uses | L-Thyroxine sodium hydrate is a useful research chemical. Its free form Thyroxine (T425600) is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia. | | Chemical Properties | almost white to beige or | | Uses | Thyroid hormone replacement. | | Definition | ChEBI: Levothyroxine sodium hydrate is an organic molecular entity. | | Brand name | Levo-T (Alara);
Levolet (Vintage); Levothroid (Lloyd); Levoxyl (Jones);
Novothyrox (Genpharm); Synthroid (Abbott); Unithroid
(Stevens J). |
| | Sodium levothyroxine Preparation Products And Raw materials |
|
