3-Pyridylboronic acid

3-Pyridylboronic acid Basic information
Product Name:3-Pyridylboronic acid
Synonyms:RARECHEM AH PB 0251;PYRIDIN-3-YLBORONIC ACID;PYRIDIN-3-BORONIC ACID;PYRIDIN-3-YL-3-BORONIC ACID;PYRIDYL-3-BORONIC ACID;Pyridine-3-boronic acid,95%;Puridin-3-yl-boronicacid;3-Pyridinylboronic acid , May contain varying amounts of anhydride, 97%
CAS:1692-25-7
MF:C5H6BNO2
MW:122.92
EINECS:605-544-8
Product Categories:Boronate Ester;Potassium Trifluoroborate;Boronic Acids and Derivatives;Chemical Synthesis;Heteroaryl Boronic Acids;Organometallic Reagents;Boronic acid series;Aromatics;Boron Derivatives;Heterocycles;Boronic Acids & Esters;Boronic Acids;Boronic Acids and Derivatives;OLED materials,pharm chemical,electronic;blocks;BoronicAcids;Pyridines;Pyridine;Boronic Acids & Esters;Boronic acids;Heterocyclic Compounds;Boronic acid;Organoborons;Aromatics Compounds;B (Classes of Boron Compounds);Heteroaryl
Mol File:1692-25-7.mol
3-Pyridylboronic acid Structure
3-Pyridylboronic acid Chemical Properties
Melting point >300 °C (lit.)
Boiling point 308.8±34.0 °C(Predicted)
density 1.22±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Slightly soluble in methanol.
pka4.00±0.10(Predicted)
form Powder, Crystals and/or Chunks
color White to yellow-orange
BRN 471943
CAS DataBase Reference1692-25-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi,C,F
Risk Statements 36/37/38-22-34-11
Safety Statements 36/37/39-3-26-45-16
WGK Germany 3
Hazard Note Irritant
HazardClass IRRITANT, KEEP COLD
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
3-Pyridylboronic acid Usage And Synthesis
Chemical PropertiesLight Yellow Powder
UsesBoronic acid derivatives and their binding affinities with diols.
Uses3-Pyridylboronic acid is a reagent used for• ;Phosphine-free Suzuki-Miyaura cross-coupling reactions
1 ;Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulation
2 ;N-arylation using copper acetylacetonate catalyst
3 ;Copper-mediated cyanation and regioselective cyanation of electron-rich benzenes
4 Reagent use in Preparation of • ;New linear poly(phenylpyridyl) chains by Suzuki coupling
5 ;Oligopyridyl foldamers as mimics of a-helix twist
6 ;Many highly significant therapeutic enzymatic and kinase inhibitors and r





Usessuzuki reaction
Synthesis Reference(s)The Journal of Organic Chemistry, 64, p. 3846, 1999 DOI: 10.1021/jo9819279
Tetrahedron Letters, 43, p. 4285, 2002
4-PYRIDYLBORONIC ACID,4-Pyridylboronic Acid (contains varying amounts of Anhydride) Sulfasalazine 6-chloro-3-pyridylboronic acid 6-(4-morpholinyl)-3-pyridinylboronic acid 2-Methoxy-5-pyridineboronic acid Ethyl 2-(Chlorosulfonyl)acetate Ascoric Acid 5-CARBOXYPYRIDINE-3-BORONIC ACID Zinc borate 2-Pyridineboronic acid Stearic acid Folic acid 3-Aminopyridine Chromium picolinate Pyridine Boric acid 3-Pyridylboronic acid Citric acid

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