3-Chloro-4-fluorophenylboronic acid

3-Chloro-4-fluorophenylboronic acid Basic information
Product Name:3-Chloro-4-fluorophenylboronic acid
Synonyms:Boronic acid,(3-chloro-4-fluorophenyl)-;Boronic acid, B-(3-chloro-4-fluorophenyl)-;3-Chloro-4-fluorobenzeneboronic acid (contains varying aMounts of anhydride);B-(3-chloro-4-fluorophenyl)-Boronic acid;(3-Chloro-4-fluorophenyl-1-yl)boronic acid;RARECHEM AH PB 0129;3-CHLORO-4-FLUOROPHENYLBORONIC ACID;3-CHLORO-4-FLUOROBENZENEBORONIC ACID
CAS:144432-85-9
MF:C6H5BClFO2
MW:174.37
EINECS:675-657-5
Product Categories:B (Classes of Boron Compounds);Boronic Acids;blocks;BoronicAcids;FluoroCompounds;Boric Acid;Fluorin-contained phenyl boronic acid series;Boronic Acid series;Substituted Boronic Acids;Benzene series;Fluorobenzene;Boronic Acid;Aryl;Organoborons
Mol File:144432-85-9.mol
3-Chloro-4-fluorophenylboronic acid Structure
3-Chloro-4-fluorophenylboronic acid Chemical Properties
Melting point 242-247 °C (lit.)
Boiling point 306.0±52.0 °C(Predicted)
density 1.41±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility soluble in Methanol
pka7?+-.0.10(Predicted)
form Powder
color Off-white to faintly orange
BRN 7369789
CAS DataBase Reference144432-85-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 36/37/38-22
Safety Statements 37/39-26-36
WGK Germany 3
HazardClass IRRITANT
HS Code 29163990
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
3-Chloro-4-fluorophenylboronic acid Usage And Synthesis
Chemical PropertiesOff-white to faintly orange powder
Usessuzuki reaction
Uses3-Chloro-4-fluorophenylboronic Acid is a reactant that has been used in the synthesis of 2-bromo-3-hexyl-5-(4-iodophenyl)thiophene, which has shown high anti-thrombolytic activity.
UsesReactant for:
  • Rh-catalyzed asymmetric addition reactions
  • Palladium-catalyzed oxidative cross-coupling reaction
  • Suzuki-Miyaura coupling
3-Chloro-4-fluorophenylboronic acid Preparation Products And Raw materials
4-CHLORO-2-FLUOROPHENYLBORONIC ACID 5-Bromo-3-chloro-2-fluorophenylboronic acid 3,4-Difluoro-5-methoxybenzeneboronic acid 2-CHLORO-6-FLUOROPHENYLBORONIC ACID 6-Bromo-3-chloro-2-fluorophenylboronic acid 5-CHLORO-2-FLUOROPHENYLBORONIC ACID 5-CHLORO-2,4-DIFLUOROPHENYLBORONIC ACID PINACOL ESTER 3-(Benzyloxy)-2-chloro-6-fluorophenylboronic acid,3-Benzyloxy-2-chloro-6-fluorophenylboronic acid 5-Chloro-2,4-difluorobenzeneboronic acid, 97% 3-CHLORO-5-FLUOROPHENYLBORONIC ACID (3-CHLORO-4-FLUORO-5-NITRO)BENZENEBORONIC ACID 2-CHLORO-4-FLUOROPHENYLBORONIC ACID 4-CHLORO-3-FLUOROPHENYLBORONIC ACID,4-CHLORO-3-FLUOROPHENYLBORONIC ACID 98% 2-CHLORO-5-FLUOROPHENYLBORONIC ACID 2-Bromo-6-chloro-5-fluorophenylboronicacid 3-CHLORO-2-FLUOROPHENYLBORONIC ACID 3-Chloro-4-fluorophenylboronic acid 2-CHLORO-3-FLUOROPHENYLBORONIC ACID

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