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Fenofibric acid

Fenofibric acid Basic information
Product Name:Fenofibric acid
Synonyms:2-[4-(4-CHLOROBENZOYL)PHENOXY]-2-METHYLPROPANOIC ACID;LABOTEST-BB LT00239222;FENOFIBRIC ACID;SALOR-INT L498335-1EA;2-[4-(4-CHLORO-BENZOYL)-PHENOXY]-2-METHYL-PROPIONIC ACID (FENOFIBRIC ACID);2-[4-(4-CHLOROBENBONYZOYL)PHENOXY)-2-METHYLPROPIONIC ACID;2-[4'-(p-Chlorobenzoyl)phenoxy]-2-methylpropionic acid;A-1081
CAS:42017-89-0
MF:C17H15ClO4
MW:318.75
EINECS:255-626-9
Product Categories:JANUVIA;Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;pharmacetical;Aromatics
Mol File:42017-89-0.mol
Fenofibric acid Structure
Fenofibric acid Chemical Properties
Melting point 177-179°C
Boiling point 486.5±35.0 °C(Predicted)
density 1.286±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka3.09±0.10(Predicted)
form powder
color White to Off-White
BRN 2058973
CAS DataBase Reference42017-89-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,N
Risk Statements 36/37/38-50/53-22
Safety Statements 26-36/37/39-61-60-24/25
RIDADR UN 3077 9 / PGIII
WGK Germany 3
RTECS UA2453000
HazardClass 9
PackingGroup III
HS Code 29189900
ToxicityLD50 oral in rat: 1242mg/kg
MSDS Information
Fenofibric acid Usage And Synthesis
Chemical PropertiesWhite to Off-White Solid
UsesFenofibric acid, the active metabolite of fenofibrate. Increases Apolipoprotein A-I–Mediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptor–dependent manner.
UsesFenofibric acid, the active metabolite of fenofibrate. Increases Apolipoprotein A-Iediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptorependent manner
UsesDPP4 inhibitor, antidiabetic
DefinitionChEBI: A monocarboxylic acid that is 2-methylpropanoic acid substituted by a 4-(4-chlorobenzoyl)phenoxy group at position 2. It is a metabolite of the drug fenofibrate.
FENOFIBRATE RELATED COMPOUND C (25 MG) (1-METHYLETHYL 2-[[2-[4-(4-CHLOROBENZOYL)PHENOXY]-2-METHYLPROPANOYL]OXY]-2-METHYLPROPANOATE) Diethyl squarate (4-Chlorophenyl)[4-(1-Methylethoxy)phenyl]Methanone (Fenofibrate IMpurity) FENOFIBRIC ACID ETHYL ESTER 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic acid methyl ester Unii-4bmh7izt98 Squaric acid 4-Chloro-4'-hydroxybenzophenone 3-[4-(4-Chlorobenzoyl)phenoxy]-2-butanone (Fenofibrate IMpurity) FENOFIBRIC ACID, HYDROXYMETHYL,Hydroxymethyl Fenofibric Acid,Hydroxymethyl Fenofibric Acid-d6 2,2-Bis(hydroxymethyl)propionic acid FENOFIBRIC ACID-D6 Ethyl 2-(Chlorosulfonyl)acetate Fenofibric Acid Acyl--D-glucuronide,Fenofibric Acid Acyl-b-D-glucuronide FENOFIBRATE IMPURITY B2[4-(4-CHLOROBENZOYL)PHENOXY]-2-METHYLPROPANOIC ACID (FENOFIBRIC ACID) EPF(CRM STANDARD) Ascoric Acid Fenofibric acid Ethoxymethylenemalononitrile
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