ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards 2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester

2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester

2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester Basic information
Product Name:2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester
Synonyms:2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester;(R)-Quinucldin-3-yl hydroxybis(2-thienyl)acetate;2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester-5;GYDFTKNRHZMENP-ZDUSSCGKSA-N;Aclidinium Bromide Impurity 5;Tiotropium Bromide Impurity 2;(R)-quinuclidin-3-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate;2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester
CAS:320347-97-5
MF:C17H19NO3S2
MW:349.46
EINECS:
Product Categories:
Mol File:320347-97-5.mol
2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester Structure
2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester Chemical Properties
Melting point 180℃ (isopropyl ether )
Boiling point 513.3±50.0 °C(Predicted)
density 1.40±0.1 g/cm3(Predicted)
pka10.33±0.29(Predicted)
Safety Information
MSDS Information
2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester Usage And Synthesis
Uses(R)-3-Quinuclidinyl di(2-thienyl)glycolate acts as a potent and long-acting muscarinic antagonist with minimal systemic exposure after inhalation. Used in the treatment of chronic obstructive pulmonary disease.
2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester Preparation Products And Raw materials
Methyl 2,2-dithienylglycolate BIS(2-THIENYL) KETONE Tiotropium bromide Impurity 16 (1α,2β,4β,5α)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7α-ol 2,3-Dibromothiophene Teloidine Ethanedioic acid,1-methyl ester, potassium salt (1:1) TiotropiuM BroMide IMpurity I 2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID Scopine Methobromide Tiotropium EP Impurity C rel-(1R,3S,5S)-8-Methyl-8-azabicyclo[3,2,1]oct-6-en-yl-2-hydroxy-2,2-dithiophen-2-yl acetate (1β,5β)-8-Methyl-8-azabicyclo[3.2.1]octa-6-ene-3α-ol Aclidinium Bromide Impurity 3（(S)-Aclidinium Bromide） 3-Phenoxypropyl bromide Ethyl 2-hydroxy-2,2-di(thiophen-2-yl)acetate tiotropium bromide hydrate Scopine-2,2-dithienyl glycolate
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