4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester

4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester Basic information
Product Name:4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester
Synonyms:4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester;3-(2-cyanoethyl) 5-Methyl 4-(2',3'-dichlorophenyl)-2,6-diMethyl-1,4-dihydropyridine-3,5-dicarboxylate;Clevidipine Butyrate iMpurity Ⅵ;Clevidipine butyrate-5;Clevidipine Butyrate Impurity 6;4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl);5-O-(2-cyanoethyl) 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) es
CAS:110962-94-2
MF:C19H18Cl2N2O4
MW:409.26
EINECS:1312995-182-4
Product Categories:Clevidipine Butyrate impurity;pharmaceutical
Mol File:110962-94-2.mol
4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester Structure
4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester Chemical Properties
Boiling point 552.6±50.0 °C(Predicted)
density 1.317±0.06 g/cm3(Predicted)
pka2.54±0.70(Predicted)
Safety Information
MSDS Information
4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester Usage And Synthesis
Uses4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-Pyridinedicarboxylic Acid 2-cyanoethyl Methyl Ester, is an impurity of Amlodipine (A633495), a dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.
4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester Preparation Products And Raw materials
Preparation Products1,4-Dihydro-2,6-dimethyl-4-(2',3'-dichlorophenyl)-5-carboxy methyl-3-pyridinecarboxylic acid
Clevidipine Clevidipine butyrate Desmethyl amolodipine diethyl 4-(2-chlorophenyl)-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)Methyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate Amlodipine Impurity 13 3,5-Pyridinedicarboxylicacid, 4-(2-chlorophenyl)-1,4-dihydro-2,6-dimethyl-, 3,5-diethyl ester Amlodipine Impurity 25 Amlodipine iMpurity K H-152/66 1,4-Dihydro-2,6-dimethyl-4-(2',3'-dichlorophenyl)-5-carboxy methyl-3-pyridinecarboxylic acid methyl 2',3'-dichloro-3-methyl-5-oxo-1,2,5,6-tetrahydro-[1,1'-biphenyl]-2-carboxylate Methanol, 1-chloro-,1-propanoate (S)-AMlodipine-d4 AMlodipine IMpurity F Maleate Amlodipine Impurity 48 d-Amlodipine Amlodipine EP Impurity D Dimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

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