11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE Basic information
Product Name:11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
Synonyms:4-PREGNEN-11BETA,17ALPHA-DIOL-3,20-DIONE;4-PREGNEN-11-BETA, 17-DIOL-3,20-DIONE;11-beta,17-alpha-dihydroxypregn-4-ene-3,20-dione;4-pregnene-11-B-17-A-diol-3-20-dione;(8S,9S,10R,13S,14S,17R)-17-acetyl-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one;11β,17α-Dihydroxy-4-pregnene-3,20-dione, 11β,17α-Dihydroxyprogesterone, 21-Desoxycortisol, 4-Pregnene-11β,17α-diol-3,20-dione;11β,17-Dihydroxypregn-4-ene-3,20-dione;C05497
CAS:641-77-0
MF:C21H30O4
MW:346.46
EINECS:211-375-7
Product Categories:Steroids;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:641-77-0.mol
11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE Structure
11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE Chemical Properties
Melting point 225-228 °C
Boiling point 523.9±50.0 °C(Predicted)
density 1.21±0.1 g/cm3(Predicted)
Fp 9℃
storage temp. -20°C
solubility Chloroform (Slightly), Methanol (Slightly, Heated)
form Solid
pka12.86±0.70(Predicted)
color White to Pale Yellow
Safety Information
Hazard Codes F,T
Risk Statements 11-23/24/25-39/23/24/25
Safety Statements 7-16-36/37-45
RIDADR UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 3
MSDS Information
11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE Usage And Synthesis
Chemical PropertiesPale Yellow Solid
UsesA metabolite of Fluticasone propionate (F599500).
Uses21-Deoxy Cortisol (Hydrocortisone EP Impurity L) is a metabolite of Fluticasone propionate (F599500).
DefinitionChEBI: 21-deoxycortisol is a deoxycortisol that is 17xi-pregn-4-ene-3,20-dione substituted by a beta-hydroxy group at position 11 and an alpha-hydroxy group at position 17. It is a marker of virilizing adrenal hyperplasia caused by 21-hydroxylase deficiency. It has a role as a human blood serum metabolite and a mouse metabolite. It is an 11beta-hydroxy steroid, a 17alpha-hydroxy-C21-steroid, a tertiary alpha-hydroxy ketone and a deoxycortisol.
11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE Preparation Products And Raw materials
6-Dehydrocortisol Hydrocortisone sodium succinate Hydrocortisone-17-butyrate 6BETA-HYDROXYCORTISOL CORTISOL (9,12,12-D3) 4-PREGNENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 21-CAPRYLATE Hydrocortisone sodium phosphate CORTISOL 17-VALERATE HYDROCORTISONE-[1,2,6,7-3H(N)] Hydrocortisone 21-hemisuccinate 4-PREGNEN-6-BETA, 11-BETA, 17,21-TETROL-3,20-DIONE 21-ACETATE 4-PREGNEN-11-BETA, 17,21-TRIOL-3,20-DIONE 21-GLUCOSIDURONATE HYDROCORTISONE CYPIONATE (200 MG) 11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE Flurandrenolide CORTISOL [1,2-3H(N)]- 4-PREGNEN-6-ALPHA, 11-BETA, 17,21-TETROL-3,20-DIONE ACETATE HYDROCORTISONE, [4-14C]

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