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| | 4-Deoxypyridoxine hydrochloride Basic information |
| | 4-Deoxypyridoxine hydrochloride Chemical Properties |
| Melting point | 274°C(dec.)(lit.) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated) | | form | neat | | color | White to Pale Red | | Stability: | Hygroscopic | | CAS DataBase Reference | 148-51-6(CAS DataBase Reference) |
| WGK Germany | 3 | | RTECS | UT4800000 | | HS Code | 29333990 | | Toxicity | LD50 oral in chicken: 1570mg/kg |
| | 4-Deoxypyridoxine hydrochloride Usage And Synthesis |
| Description | 4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities. It inhibits transport of pyridoxine , pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells. DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells. DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos. It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy. DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis. | | Chemical Properties | Solid | | Uses | 4-Deoxypyridoxine is the deoxy analogue of Pyridoxine (P991735). 4-Deoxypyridoxine is a vitamin B6 antimetabolite; 4-Deoxypyridoxine can induce a deficient status that alters the function and ultrastructure of EC similar to vascular disease. |
| | 4-Deoxypyridoxine hydrochloride Preparation Products And Raw materials |
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