2-Ethylhexyl salicylate

2-Ethylhexyl salicylate Basic information
Product Name:2-Ethylhexyl salicylate
Synonyms:SALICYLIC ACID 2-ETHYLHEXYL ESTER;TIMTEC-BB SBB008473;2-ETHYLHEXYL SALICYLATE 99+%;SALICYLIC ACID 2-ETHYLHEXYL ESTER 98+%;OCTISALATE,USP;2-Ethylhexylsalicylat;2-hydroxy-benzoic acid 2-ethylhexyl ester;2-ETHYLHEXYL SALICYLATE, 98+%
CAS:118-60-5
MF:C15H22O3
MW:250.33
EINECS:204-263-4
Product Categories:cosmetic raw material;UV-Absorber;118-60-5
Mol File:118-60-5.mol
2-Ethylhexyl salicylate Structure
2-Ethylhexyl salicylate Chemical Properties
Boiling point 189-190 °C/21 mmHg (lit.)
density 1.014 g/mL at 25 °C (lit.)
vapor pressure 0.018Pa at 20℃
refractive index n20/D 1.502(lit.)
Fp >230 °F
storage temp. Refrigerator
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
pka8.13±0.30(Predicted)
form neat
color A colourless liquid.
Odorat 100.00 %. mild orchid sweet balsam
Odor Typefloral
Water Solubility 74.4μg/L at 20℃
Merck 14,6770
BRN 2730664
LogP5.94 at 25℃
CAS DataBase Reference118-60-5(CAS DataBase Reference)
NIST Chemistry ReferenceSalicylic acid, 2-ethylhexyl ester(118-60-5)
EPA Substance Registry System2-Ethylhexyl salicylate (118-60-5)
Safety Information
Risk Statements 36/37/38
Safety Statements 26-36/37/39
WGK Germany -
RTECS VO3150000
HS Code 2918230000
ToxicityLD50 intraperitoneal in mouse: 200mg/kg
MSDS Information
ProviderLanguage
SigmaAldrich English
2-Ethylhexyl salicylate Usage And Synthesis
Chemical Propertiesliquid
OccurrenceHas apparently not been reported to occur in nature.
Usesoctisalate is a uVB protector. This is the drug name for ethylhexyl salicylate and octyl salicylate.
Usesethylhexyl salicylate is an FDA-approved uVB sunscreen chemical, it absorbs within the entire uVB range. It has an approved usage level of 3 to 5 percent in both the united States and the european union, and is a good solubilizer for benzophenone-3. In suntan lotions, it is used as a preservative and anti-microbial. This is a salt of salicylic acid occurring in wintergreen leaves and in other plants. It is also synthetically manufactured. It is considered a non-comedogenic raw material. This is the InCI name for octyl salicylate.
UsesSolvent for solid sunscreens.
Uses2-ethylhexyl salicylate is also known as ethylhexyl salicylate and octyl salicylate. It is a uVB absorber.
DefinitionChEBI: Ethylhexyl salicylate is a benzoate ester and a member of phenols. It is functionally related to a salicylic acid.
PreparationFrom 2-ethylhexanol and salicylic acid by azeotropic-type esterification (Arctander, 1969).
Brand nameEscalol (ISP Van Dyk); Neo Heliopan (Haarmann & Reimer, Germany); Uvinul (BASF). Note—The International Cosmetic Ingredient (INCI) name for octisalate is octyl salicylate.
General Description2-Ethylhexyl salicylate(EHS) is an organic ultraviolet(UV) absorber that can be used as a photostable ingredient in cosmetic formulations. It shows an absorption spectra in the range of 280-320 nm in the UV region.
Flammability and ExplosibilityNonflammable
2-Ethylhexyl salicylate Preparation Products And Raw materials
Cefuroxime 1-acetoxyethyl ester 8''-hydroxypactamycin 2-ETHYLHEXYL PALMITATE 2-Ethylhexyl mercaptoacetate FENCHYL SALICYLATE MENTHYL SALICYLATE Hexyl salicylate Octyldodecyldimethylammonium chloride ARSENIC ACID TRIETHYL ESTER Acetic acid octyl ester Isochlortetracyclinehydrochloride ALPHA-APO-OXYTETRACYCLINE BENZOIC ACID 2-ETHYLHEXYL ESTER 2-Ethylhexyl salicylate Isoamyl o-hydroxybenzoate Phenyl salicylate Dioctyl terephthalate Sodium sulfosalicylate Ethylhexyl Salicylate

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