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| | 6,6'-DITHIODINICOTINIC ACID Basic information |
| Product Name: | 6,6'-DITHIODINICOTINIC ACID | | Synonyms: | 6,6’-dithiobis-3-pyridinecarboxylicaci;6,6’-dithionicotinicacid;carboxypyridinedisulfide;cpds;6,6'-DITHIOBIS(3-PYRIDINECARBOXYLIC ACID);6,6'-DITHIODINICOTINIC ACID;6-[(5-CARBOXY-2-PYRIDYL)DITHIO]NICOTINIC ACID;6,6'-DITHIODINICOTINIC ACID, TECH., 85% | | CAS: | 15658-35-2 | | MF: | C12H8N2O4S2 | | MW: | 308.33 | | EINECS: | 239-729-6 | | Product Categories: | Heterocyclic Compounds | | Mol File: | 15658-35-2.mol |  |
| | 6,6'-DITHIODINICOTINIC ACID Chemical Properties |
| Melting point | 263-265 °C(lit.) | | Boiling point | 584.2±50.0 °C(Predicted) | | density | 1.66±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | pka | 2.82±0.10(Predicted) | | form | powder to crystal | | color | White to Light yellow | | Stability: | Stable. Incompatible with strong oxidizing agents. | | CAS DataBase Reference | 15658-35-2(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 | | RTECS | US5684700 | | HS Code | 2933399990 |
| | 6,6'-DITHIODINICOTINIC ACID Usage And Synthesis |
| Chemical Properties | tan powder | | Uses | 6,6′-Dithiodinicotinic acid may be employed as:
- specific thiol blocker to investigate the radioprotective effect of mercaptoethylamine on the thiol level of the outer cell membrane of the Ehrlich ascites tumor cells
- modifier to investigate the polar microenvironment around the reactive Cys283 of rabbit muscle creatine kinase
- dipyridyl-dithio substrate to evaluate the protein disulfide-thiol interchange activity of the auxin stimulated NADH: protein disulfide reductase (NADH oxidase) of soybean plasma membranes
- water-soluble reagent in a study for introducing, in buffered saline, a reactive sulfhydryl group on water-soluble molecules bearing an alkyl-amino group
- chromogen for sulfhydryl groups in the Ellman method for cholinesterase determinations
- spectrophotometric determination of thiols and of total glutathione in human blood
| | General Description | 6,6′-Dithiodinicotinic acid is reported as sulphydryl reagent. 6,6′-Dithiodinicotinic acid is reported to react with thiols, to afford a disulfide and 6-mercaptonicotinic acid. Interaction of 6,6′-dithiodinicotinic acid with the homogenates of Ehrlich ascites cells has been reported. |
| | 6,6'-DITHIODINICOTINIC ACID Preparation Products And Raw materials |
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