|  | |  |  | ACETYLSALICYLSALICYLIC ACID Basic information | 
|  |  | ACETYLSALICYLSALICYLIC ACID Chemical Properties | 
 | Melting point | 153-160 °C |  | Boiling point | 361.5°C (rough estimate) |  | density | 1.346 |  | refractive index | 1.4600 (estimate) |  | storage temp. | Sealed in dry,Room Temperature |  | solubility | Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly) |  | form | neat |  | pka | 2.94±0.36(Predicted) |  | color | White to Off-White |  | Water Solubility | 20mg/L(21 ºC) |  | EPA Substance Registry System | 2-Carboxyphenyl 2-(acetyloxy)benzoate (530-75-6) | 
| Hazard Codes | Xi |  | Risk Statements | 36/37/38 |  | Safety Statements | 24/25 |  | HS Code | 29182900 | 
| Provider | Language |  
| ACROS | English |  |  |  | ACETYLSALICYLSALICYLIC ACID Usage And Synthesis | 
 | Chemical Properties | white to almost white fine crystalline powder |  | Uses | Antiinflammatory;Cyclooxygenase inhibitor |  | Uses | analgesic, antipyretic |  | Uses | Acetylsalicylic Acid Impurity C |  | Definition | ChEBI: 2-[(2-acetyloxyphenyl)-oxomethoxy]benzoic acid is a carbonyl compound. |  | Purification Methods | Crystallise the analgesic from dilute AcOH or EtOH (m 161-162o), MeOH (m 165-168o), and *C6H6/EtOH (m 163-165o). Its solubilities in boiling Et2O, *C6H6 and EtOH are 1.4%, 2.2% and 33%, respectively. [Baker et al. J Chem Soc 201 1951, Garrett et al. J Am Pharm Soc 48 684 1959, Beilstein 10 I 41, 10 II 54, 10 IV 165.] | 
|  |  | ACETYLSALICYLSALICYLIC ACID Preparation Products And Raw materials | 
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