4-Chloropyridine-2-carboxylic acid

4-Chloropyridine-2-carboxylic acid Basic information

Product Name:	4-Chloropyridine-2-carboxylic acid
Synonyms:	IFLAB-BB F1926-0017;4-CHLOROPICOLINIC ACID;4-CHLOROPYRIDINE-2-CARBOXYLIC ACID;4-CHLORO-2-PYRIDINECARBOXYLIC ACID;4-Chloropyridine-2-carboxylic;Chloropicolinicacid;4-CHLOROPICOLINIC ACID 99%;4-Chloropicolinic acid ,98%
CAS:	5470-22-4
MF:	C6H4ClNO2
MW:	157.55
EINECS:	676-597-2
Product Categories:	Chloropyridines;Halopyridines;pharmacetical;Carboxylic Acids;Pyridine;Carboxylic Acids;blocks;Carboxes;Pyridines;Pyridine series;Acids and Derivatives;Heterocycles
Mol File:	5470-22-4.mol

4-Chloropyridine-2-carboxylic acid Chemical Properties

Melting point	181°C
Boiling point	308.0±22.0 °C(Predicted)
density	1.470±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder to crystal
pka	3.27±0.10(Predicted)
color	White to Almost white
CAS DataBase Reference	5470-22-4(CAS DataBase Reference)

Safety Information

MSDS Information

4-Chloropyridine-2-carboxylic acid Usage And Synthesis

Chemical Properties	White solid
Uses	4-Chloropicolinic Acid is a reactant used in the synthesis of VU0431316, a negative allosteric modulator of mGlu5.

4-Chloropyridine-2-carboxylic acid Preparation Products And Raw materials

Raw materials	Hydrochloric acid-->Acetic acid-->Nitric acid-->Sodium carbonate-->Hydrogen peroxide-->Potassium permanganate-->FUMING SULFURIC ACID-->2-Picoline-->2-Methyl-4-nitropyridine-->2-Pyridinecarboxylicacid,4,5,6-trichloro--->4,6-Dichloro-2-pyridinecarboxylic acid-->2-Picolinic acid-->Thionyl chloride
Preparation Products	2-Bromo-4-chloropyridine-->4-Ethoxy-2-pyridinecarboxylic acid ethyl ester

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