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| | 4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one Basic information |
| Product Name: | 4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one | | Synonyms: | 4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one;4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one-S-oxide;Lamivudine EP Impurity G;Lamivudine Impurity 8(Lamivudine EP Impurity H);2(1H)-Pyrimidinone,4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]- (9CI);2(1H)-Pyrimidinone, 4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-;4-Amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone;Lamivudine EP Impurity H / R Sulfoxide | | CAS: | 160552-54-5 | | MF: | C8H11N3O4S | | MW: | 245.26 | | EINECS: | | | Product Categories: | | | Mol File: | 160552-54-5.mol |  |
| | 4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one Chemical Properties |
| Boiling point | 601.7±65.0 °C(Predicted) | | density | 1.93±0.1 g/cm3(Predicted) | | solubility | DMSO (Slightly, Heated), Water (Slightly, Heated, Sonicated) | | form | Solid | | pka | 13.46±0.10(Predicted) | | color | White to Off-White | | Stability: | Hygroscopic |
| | 4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one Usage And Synthesis |
| Uses | Lamivudine (R)-Sulfoxide (Lamivudine EP Impurity H) is a metabolite of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B. |
| | 4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one Preparation Products And Raw materials |
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