DMT-dG(ib) Phosphoramidite

DMT-dG(ib) Phosphoramidite Basic information
Product Name:DMT-dG(ib) Phosphoramidite
Synonyms:dG(N-ibu) Phosphoramidite;N-blocked-5'-O-DMT 3'-CED deoxyguanosine phosphoramidite;5'-O-(4,4-Dimethoxytrityl)-N-isobutyryl-2'-deoxyguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite;5'-O-(4,4'-DIMETHOXYTRITYL)-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE;N2-(ISOBUTYRYL)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE;deoxyguanosine-ce phosphoramidite*for cyclone;DNA G Phosphoramidite;DMT-dG(dmf) Amidite 5g, Single
CAS:93183-15-4
MF:C44H54N7O8P
MW:839.92
EINECS:685-519-6
Product Categories:Pharmaceutical;RNAi
Mol File:93183-15-4.mol
DMT-dG(ib) Phosphoramidite Structure
DMT-dG(ib) Phosphoramidite Chemical Properties
density 1.22 at 20℃
vapor pressure 0-0Pa at 20-50℃
storage temp. Sealed in dry,2-8°C
solubility soluble, clear
pka9.16±0.20(Predicted)
form powder or granules
color white to off-white
InChIKeyFDRMKYVTIFSDPR-MMROLVBFSA-N
SMILESC(OC[C@H]1O[C@@H](N2C=NC3C(=O)NC(NC(=O)C(C)C)=NC2=3)C[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C)(C1=CC=CC=C1)(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1 |&1:3,5,23,r|
LogP4.17 at 20℃
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29349990
MSDS Information
DMT-dG(ib) Phosphoramidite Usage And Synthesis
Uses2’-Deoxy-5’-O-DMT-N2-isobutyrylguanosine 3’-CE Phosphoramidite is used to prepare antisense oligonucleotides containing conformationally constrained methoxyaminomethylene and aminooxymethylene and aminomethylene bridged nucleoside analogs.
DMT-dG(ib) Phosphoramidite Preparation Products And Raw materials
O1-(DIMETHOXYTRITYL)PROPANE-1,3-DIOL (+/-)-1-TERT-BUTYLGLYCEROL 5'-O-(4,4'-DIMETHOXYTRITYL)-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE-3'-(METHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE N2-Isobutyryl-2'-deoxyguanosine N2-ISOBUTYL-DG CEP Guanine 5-O-(DIMETHOXYTRITYL)-1,2-DIDEOXY-D-RIBOSE N2-(ISOBUTYRYL)-5'-O-(DIMETHOXYTRITYL)-2'-O-(T-BUTYLDIMETHYLSILYL)-GUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE 3-(4,4'-DIMETHOXYTRITYL)PROPANDIOL-1-N,N-DIISOPROPYL (BETA-CYANOETHYL) PHOSPHORAMIDITE 9-ETHYLGUANINE 5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine Dimethyl N,N-Diethyl Phosphoramidite 5'-O-(DIMETHOXYTRITYL)-N2-ETHYL-2'-DEOXYGUANOSINE 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-*DEOXYGUA NOSINE Acyclovir N,N'-methylenediacetamide N2-METHYL-DG CEP N2-METHYL-2'-DEOXYGUANOSINE

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