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| | CAPRIC ACID SODIUM SALT Basic information |
| Product Name: | CAPRIC ACID SODIUM SALT | | Synonyms: | caprinicacidsodiumsalt;sodiumdecanoicacid;DECANOIC ACID SODIUM SALT;CAPRIC ACID SODIUM SALT;capric acid sodium;N-DECANOIC ACID SODIUM SALT;N-CAPRIC ACID SODIUM SALT;SODIUM DECANOATE | | CAS: | 1002-62-6 | | MF: | C10H19NaO2 | | MW: | 194.25 | | EINECS: | 213-688-4 | | Product Categories: | | | Mol File: | 1002-62-6.mol |  |
| | CAPRIC ACID SODIUM SALT Chemical Properties |
| Melting point | ~240 °C (dec.) | | storage temp. | 2-8°C | | solubility | H2O: 0.1 g/mL, clear, colorless | | form | powder to crystal | | color | White to Light yellow | | Water Solubility | very faint turbidity | | BRN | 3572742 | | LogP | 3.965 (est) | | CAS DataBase Reference | 1002-62-6(CAS DataBase Reference) | | EPA Substance Registry System | Sodium decanoate (1002-62-6) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | HE0200000 | | HS Code | 2915.90.5050 |
| | CAPRIC ACID SODIUM SALT Usage And Synthesis |
| Description | Decanoic acid is a medium-chain saturated fatty acid. It is a non-competitive antagonist at AMPA receptors that selectively reduces glutamate-induced currents in Xenopus oocytes expressing GluA2 and GluA3 subunit-containing AMPA receptors (IC50 = 0.52 mM) over those expressing GluA1 (IC50 = 2.09 mM) or GluA1 and GluA2 subunits (IC50 = 1.16 mM). It inhibits epileptiform activity induced by pentylenetetrazole or low magnesium in rat hippocampal slices. Decanoic acid (1 mM) induces contractions in isolated guinea pig duodenum, an effect that can be blocked by the muscarinic acetylcholine receptor antagonist hyoscine, voltage-gated sodium channel inhibitor tetrodotoxin (Item Nos. 14964 | 14963), or M2 muscarinic acetylcholine receptor antagonist hexamethonium . It increases the escape threshold in an orofacial mechanical stimulation test in rats when administered at a topical dose of 30% in ointment form, indicating analgesic activity. This effect can be blocked by the muscarinic acetylcholine receptor antagonist methoctramine . Plasma levels of decanoic acid are increased in patients with colorectal cancer when compared to patients with breast cancer or ulcerative colitis or without cancer. | | Uses | Sodium Caprate is the sodium salt of capric acid. It functions as a binder, emulsifier, and anticaking agent. | | Purification Methods | Neutralise sodium hydroxide by adding a slight excess of free decanoic acid and recovering the excess acid by Et2O extraction. The salt is recrystallised from the aqueous solution by adding pure acetone and repeating the steps several times, then drying the salt in an oven at ca 110o [Chaudhury & Awuwallia Trans Faraday Soc 77 3119 1981]. [Beilstein 2 IV 1041.] |
| | CAPRIC ACID SODIUM SALT Preparation Products And Raw materials |
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