ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards 1-ETHYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID

1-ETHYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID

1-ETHYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID Basic information
Product Name:1-ETHYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
Synonyms:7-chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinolind-3-carboxylic acid;Norfloxacin EP Impurity A;7-CHLORO-1,4-DIHYDRO-1-ETHYL-6-FLUORO-4-OXO-3-QUINOLINECARBOXYLIC ACID;7-CHLORO-1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINE CARBOXYLIC ACID;7-CHLORO-1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO QUINOLINE-3-CARBOXYLIC ACID;7-CHLORO-1-ETHYL-6-FLUORO-4-OXOHYDROQUINOLINE-3-CARBOXYLIC ACID;AKOS 1303;1-ETHYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
CAS:68077-26-9
MF:C12H9ClFNO3
MW:269.66
EINECS:614-262-4
Product Categories:Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:68077-26-9.mol
1-ETHYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID Structure
1-ETHYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID Chemical Properties
Melting point 245°C
Boiling point 437.9±45.0 °C(Predicted)
density 1.3905 (estimate)
storage temp. Sealed in dry,2-8°C
solubility DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka-0.21±0.20(Predicted)
form neat
color White to Pale Yellow
InChIKeyWNNSMMJBBOPPOT-UHFFFAOYSA-N
CAS DataBase Reference68077-26-9(CAS DataBase Reference)
Safety Information
Risk Statements 52/53
Safety Statements 61
HazardClass IRRITANT
HS Code 2933599550
MSDS Information
ProviderLanguage
ACROS English
ALFA English
1-ETHYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID Usage And Synthesis
Chemical PropertiesWhite powder
Uses7-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid (Norfloxacin EP Impurity A) is a Norfloxacin intermediate. Norfloxacin EP Impurity A; Norfloxacin USP Related Compound A (7-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid).
1-ETHYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID Preparation Products And Raw materials
Norfloxacin EP Impurity C Norfloxacin EP Impurity G Norfloxacin EP Impurity D 6-Fluoro-1,4-dihydro-1-methyl-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid Norfloxacin Impurity 2 Norfloxacin EP Impurity H Norfloxacin EP Impurity E Desethylene Norfloxacin Hydrochloride 6-Chloro-1-Ethyl-4-Oxo-7-(Piperazin-1-yl)-1,4-Dihydroquinoline-3-Carboxylic acid METHYL 7-CHLORO-6-FLUORO-1-CYCLOPROPYL-1,4-DIHYDROGEN-4-OXO-3-QUINOLINE CARBOXYLATE 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID AKOS 92521 3-Quinolinecarboxylic acid AKOS 94413 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid 1-ETHYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER AKOS 1306
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