ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Pyridine derivatives 2-Chloro-5-fluoronicotinic acid

2-Chloro-5-fluoronicotinic acid

2-Chloro-5-fluoronicotinic acid Basic information
Product Name:2-Chloro-5-fluoronicotinic acid
Synonyms:3-Pyridinecarboxylic acid, 2-chloro-5-fluoro-;2-chloro -5-fluorinenicotinic acid;2--5-fluorinechlorinenicotinic acid;2-chloro-5-fluoronicotinic;2-Chloro-5-fluoropyridine-3-carboxylic acid, 3-Carboxy-2-chloro-5-fluoropyridine;2-Chloro-5-fluoropyridine-3-carboxylic acid technical grade;2-CHLORO-5-FLUOROPYRIDINE-3-CARBOXYLIC ACID;2-CHLORO-5-FLUORONICOTINIC ACID
CAS:38186-88-8
MF:C6H3ClFNO2
MW:175.54
EINECS:
Product Categories:C5 to C6;C6 to C7;Chemical Synthesis;Fluorinated Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyridine;Pyridines, Pyrimidines, Purines and Pteredines;pharmacetical;Pyridines;Building Blocks;Boronic Acid;Heterocyclic Fluorinated Building Blocks;Other Fluorinated Heterocycles
Mol File:38186-88-8.mol
2-Chloro-5-fluoronicotinic acid Structure
2-Chloro-5-fluoronicotinic acid Chemical Properties
Melting point 141-142°C
Boiling point 297.0±35.0 °C(Predicted)
density 1.576±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka1.67±0.25(Predicted)
form powder
color Off-white
InChIKeyWMADTZFXZAITIR-UHFFFAOYSA-N
CAS DataBase Reference38186-88-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 7/9-24/25-26-36/37-38-51
WGK Germany 3
HazardClass IRRITANT
HS Code 2933399990
MSDS Information
2-Chloro-5-fluoronicotinic acid Usage And Synthesis
Synthesis Reference(s)The Journal of Organic Chemistry, 71, p. 4021, 2006 DOI: 10.1021/jo0602571
2-Chloro-5-fluoronicotinic acid Preparation Products And Raw materials
Preparation ProductsMETHYL2-CHLORO-5-FLUORONICOTINATE-->2-Chloro-5-fluoronicotinonitrile-->2-CHLORO-5-FLUORO-3-PYRIDINECARBONYL CHLORIDE
Cyhalothrin 5-CHLORO-2-FLUORONICOTINIC ACID Flucloxacillin sodium QUINOLINE-3-CARBOXYLIC ACID Ethyl 2-(Chlorosulfonyl)acetate Chloroacetic acid 2-CHLORO-5-FLUORONICOTINIC ACID ETHYL ESTER Difluorochloromethane 5-Fluoronicotinic acid 2-Chloro-5-fluoronicotinic acid ethyl ester 5-chloro-6-fluoronicotinic acid 2-CHLORO-4-FLUORONICOTINIC ACID 2-Chloro-5-fluoronicotinic acid 3-Chloro-2-fluoropyridine-4-carboxylic acid Cyhalothrin Epichlorohydrin Fluroxypyr Flucloxacillin
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