|
| | Swertiamarine Basic information |
| Product Name: | Swertiamarine | | Synonyms: | (4ar-(4a-alpha,5-beta,6-alpha))-ranosyloxy)-4a-hydroxy;1h,3h-pyrano(3,4-c)pyran-1-one,4,4a,5,6-tetrahydro-5-ethenyl-6-(beta-d-glucopy;1H,3H-Pyrano[3,4-c]pyran-1-one,4,4.alpha.,5,6-tetrahydro-5-ethenyl-6-(.beta.-D-glucopyranosyloxy)-4.alpha.-hydroxy-,[4ar-(4.alpha.-.alpha.,5-.beta.,D-.alpha.)]-;3H-Pyrano[3,4-c]pyran-1-one,4,4.alpha.,5,6-tetrahydro-5-ethenyl-6-(.beta.-D-glucopyranosyloxy)-4.1H;Swertiamari;4-c)pyran-1-one,4,4a,5,6-tetrahydro-5-ethenyl-6-(beta-d-glucopyranosyloxy)-4a-hydroxy-3h-pyrano(1;glucopyranosyloxy)-4,4a,5,6-tetrahydro-4a-hydroxy-,(4aR,5R, 6S)-;Swertiamarin(6CI,7CI,8CI) | | CAS: | 17388-39-5 | | MF: | C16H22O10 | | MW: | 374.34 | | EINECS: | | | Product Categories: | Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Sugars, Carbohydrates & Glucosides | | Mol File: | 17388-39-5.mol |  |
| | Swertiamarine Chemical Properties |
| Melting point | 113-114° | | alpha | D20 -127° (c = 1 in 96% ethanol) | | Boiling point | 649.3±55.0 °C(Predicted) | | density | 1.57±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | DMSO : 250 mg/mL (667.84 mM; Need ultrasonic) | | pka | 11.56±0.60(Predicted) | | form | neat | | color | White to Yellow to Orange | | λmax | 238nm(MeOH)(lit.) | | Merck | 14,9010 | | BRN | 55278 | | Stability: | Hygroscopic | | InChIKey | HEYZWPRKKUGDCR-QBXMEVCASA-N | | CAS DataBase Reference | 17388-39-5(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | RTECS | UQ1366700 | | HS Code | 29389090 | | Toxicity | mouse,LD50,intraperitoneal,> 8gm/kg (8000mg/kg),BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 13, Pg. 464, 1982. |
| | Swertiamarine Usage And Synthesis |
| Uses | Swertimarine is an extract from Enicostemma littorale which is an herb used in the treatment of type 1 and 2 diabetes. Used to sensitize the cells to hypolipidemic conditions and insulin. | | Definition | ChEBI: Swertiamarin is a glycoside. |
| | Swertiamarine Preparation Products And Raw materials |
|
