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| | cis-Atovaquone Basic information |
| Product Name: | cis-Atovaquone | | Synonyms: | Atovaquone EP Imp B;Atovaquone Impurity 2（Atovaquone EP Impurity B）;Atovaquone EP Impurity B (RC A);cis-Atovaquone-d4;cis-Atovaquone;1,4-Naphthalenedione,2-[cis-4-(4-chlorophenyl)cyclohexyl]-3- hydroxy-;Atovaquone EP Impurity B (Atovaquone Related Compound A);2-((1s,4s)-4-(4-chlorophenyl)cyclohexyl)-3-
hydroxynaphthalene-1,4-dione | | CAS: | 137732-39-9 | | MF: | C22H19ClO3 | | MW: | 366.84 | | EINECS: | | | Product Categories: | Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals | | Mol File: | 137732-39-9.mol |  |
| | cis-Atovaquone Chemical Properties |
| Melting point | >40°C (dec.) | | Boiling point | 535.0±50.0 °C(Predicted) | | density | 1.349±0.06 g/cm3(Predicted) | | storage temp. | Room Temperature, under inert atmosphere | | solubility | Chloroform (Slightly), Dichloromethane (Slightly, Acetonitrile) | | pka | 5.01±0.10(Predicted) | | form | Solid | | color | Pale Yellow to Light Yellow |
| | cis-Atovaquone Usage And Synthesis |
| Uses | cis-Atovaquone is the cis-isomer of Atovaquone (A793500), a hydroxynaphthoquinone derivative that inhibits mitochondrial electron transport. | | Definition | ChEBI: Atovaquone is a naphthoquinone compound having a 4-(4-chlorophenyl)cyclohexyl group at the 2-position and a hydroxy substituent at the 3-position. It has a role as an antimalarial, an antifungal agent, an EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor, an EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor and an EC 1.10.2.2 (quinol--cytochrome-c reductase) inhibitor. It is a member of monochlorobenzenes and a hydroxy-1,4-naphthoquinone. |
| | cis-Atovaquone Preparation Products And Raw materials |
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