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| | CYTOCHALASIN C Basic information |
| Product Name: | CYTOCHALASIN C | | Synonyms: | (11)cytochalasa-5,13,19-triene-1,17-dione,21-(acetoxy)-7,18-dihydroxy-16,18-di;(7s,13e,16s,18r,19e,21r)-methyl-10-phenyl;CYTOCHALASIN C;cytochalasin C from metarrhizium anisopliae;cytochalasin-C from metarrhizium*anisopliae;CYTOCHALASIN C(RG);7(S),18-dihydroxy-16(S),18(R)-dimethyl-10-phenyl[11]cytochalasa-5,13(E),19(E)-triene-1,17-dione 21(R)-acetate;CYTOCHALASIN C FROM METARRHIRIUM ANISOPL IAE | | CAS: | 22144-76-9 | | MF: | C30H37NO6 | | MW: | 507.62 | | EINECS: | 244-803-6 | | Product Categories: | antibiotic;Enzyme Inhibitors;Enzyme Inhibitors by Type;Other | | Mol File: | 22144-76-9.mol |  |
| | CYTOCHALASIN C Chemical Properties |
| Melting point | 260-264°C | | Boiling point | 595.84°C (rough estimate) | | density | 1.1764 (rough estimate) | | refractive index | 1.6310 (estimate) | | storage temp. | −20°C | | solubility | methylene chloride: 5 mg/mL, clear, colorless | | form | White to off-white powder. | | pka | 11.95±0.70(Predicted) | | BRN | 1613194 | | LogP | 3.250 (est) |
| Hazard Codes | T+,T | | Risk Statements | 26/27/28-63 | | Safety Statements | 28-36/37-45 | | RIDADR | UN 1544 6.1/PG 2 | | WGK Germany | 3 | | RTECS | HA5300500 | | F | 10 | | HazardClass | 6.1(a) | | PackingGroup | I | | HS Code | 29337900 | | Toxicity | mouse,LD,intraperitoneal,> 100mg/kg (100mg/kg),Chemical and Pharmaceutical Bulletin. Vol. 21, Pg. 2268, 1973. |
| | CYTOCHALASIN C Usage And Synthesis |
| Chemical Properties | White solid | | Uses | Cytochalasin C, a fungal metabolite, is an analog of Cytochalasin D (C998700), an anti-hypertensive drug acting on human intestinal epithelial caco-2 cells. Also has activity in HMG-CoA reductase inhibitors used in the lowering of cholesterol. Actin inhibitor, actin polymerization inhibitor affecting cell movement, growth, phagocytosis and even secretion. | | Uses | Cytochalasin C is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, resulting in pronounced morphogenic changes in animals and plants. The cytochalasins act by disrupting actin microfilaments and these effects are most noticeable by the inhibition of cell division. |
| | CYTOCHALASIN C Preparation Products And Raw materials |
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