Ethyl picolinate

Ethyl picolinate Basic information
Product Name:Ethyl picolinate
Synonyms:Pyridine-2-A Ethyl;Ethyl Picolinate Picolinic Acid Ethyl Ester Pyridine-2-carboxylic Acid Ethyl Ester;ETHYL 2-PYRIDINECARBOXYLATE FOR SYNTHESI;Ethyl picolinate, 99% 100ML;ETHYL PICOLINATE;ETHYL PYRIDINE-2-CARBOXYLATE;ETHYL 2-PYRIDINECARBOXYLATE;ETHYL 2-PICOLINATE
CAS:2524-52-9
MF:C8H9NO2
MW:151.16
EINECS:219-758-0
Product Categories:Aromatics;Heterocycles;CARBOXYLICESTER;GLYCINESCAFFOLD;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatic Esters;Acids & Esters;Miscellaneous Compounds
Mol File:2524-52-9.mol
Ethyl picolinate Structure
Ethyl picolinate Chemical Properties
Melting point 2 °C (lit.)
Boiling point 240-241 °C (lit.)
density 1.119 g/mL at 25 °C (lit.)
refractive index n20/D 1.511(lit.)
Fp 225 °F
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Sparingly), Methanol (Slightly)
form Liquid
pka1.83±0.10(Predicted)
color Clear yellow or pink
Water Solubility miscible
BRN 122485
InChIKeyFQYYIPZPELSLDK-UHFFFAOYSA-N
LogP0.870
CAS DataBase Reference2524-52-9(CAS DataBase Reference)
NIST Chemistry Reference2-Pyridinecarboxylic acid, ethyl ester(2524-52-9)
EPA Substance Registry SystemEthyl picolinate (2524-52-9)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
TSCA Yes
HS Code 29333999
MSDS Information
ProviderLanguage
Ethyl pyridine-2-carboxylate English
ACROS English
SigmaAldrich English
ALFA English
Ethyl picolinate Usage And Synthesis
Chemical Propertiesclear yellowish or pink liquid
UsesEthyl picolinate can be used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors and their preparation and use in the treatment of diabetes.
UsesEthyl picolinate is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors which is used in the treatment of diabetes. It is also used as pharmaceutical intermediate.
Synthesis Reference(s)Chemical and Pharmaceutical Bulletin, 43, p. 1028, 1995 DOI: 10.1248/cpb.43.1028
Ethanol Diphenolic acid Ethyl formate 4-(Diethylamino)salicylaldehyde Urethane Ethylbenzene Ethylparaben CHLOROETHANE DL-α-Tocopherol Ethyl chloroformate Ethyl cellulose Ethyl isonicotinate Diethyl ether Ethyl acetate Ethyl acrylate Pyridine Ethyl cyanoformate RESMETHRIN

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