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| | Salvianolic acid Basic information |
| Product Name: | Salvianolic acid | | Synonyms: | (2R)-3-(3,4-Dihydroxyphenyl)-2-[(E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]prop-2-enoyl]oxypropanoic acid;SALVIANOLIC ACID A 98.0% BY HPLC;Danphenolic acid A;(R)-3-(3,4-Dihydroxyphenyl)-2-(((E)-3-(2-((E)-3,4-dihydroxystyryl)-3,4-dihydroxyphenyl)acryloyl)o;Salvianolic acid A, froM Salvia Miltiorrhiza;(R)-3-(3,4-Dihydroxyphenyl)-2-(((E)-3-(2-((E)-3,4-dihydroxystyryl)-3,4-dihydroxyphenyl)acryloyl)oxy)propanoic acid;(αR)-α-[[(2E)-3-[2-[(1E)-2-(3,4-Dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxybenzenepropanoic acid;Dan phenolic acid A hydrate | | CAS: | 96574-01-5 | | MF: | C26H22O10 | | MW: | 494.45 | | EINECS: | | | Product Categories: | chemical reagent;pharmaceutical intermediate;Aromatics;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 96574-01-5.mol |  |
| | Salvianolic acid Chemical Properties |
| Melting point | 164-167°C | | Boiling point | 858.7±65.0 °C(Predicted) | | density | 1.580±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | H2O: ≥19mg/mL | | pka | 2.78±0.10(Predicted) | | form | powder | | color | yellow | | BRN | 2660108 | | InChIKey | YMGFTDKNIWPMGF-UCPJVGPRSA-N |
| Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29189900 |
| | Salvianolic acid Usage And Synthesis |
| Description | Salvianolic acid A is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza that has been investigated for its cardioprotective and chemopreventative properties. It has been reported to reduce leukocyte-endothelial adherence, as well as inhibit inflammation and matrix metalloproteinases, suppress apoptosis, and reduce lipid peroxidation in damaged cardiac tissue. | | Chemical Properties | Yellow Solid | | Uses | ISalvianolic acid A (Sal A) and salvianolic acid B (Sal B) were isolated and purified from the crude extract of Salvia miltiorrhiza. Antioxidant activities of Sal A and Sal B were also evaluated
the ABTS results showed that Sal A and Sal B exhibited high total antioxidant activities, their EC50 values were 1.35 0.00 and 1.43 0.01 .mu.g/mL. | | Uses | ISalvianolic acid A (Sal A) and salvianolic acid B (Sal B) were isolated and purified from the crude extract of Salvia miltiorrhiza. Antioxidant activities of Sal A and Sal B were also evaluated and the ABTS results showed that Sal A and Sal B exhibited high total antioxidant activities, their EC50 values were 1.35 0.00 and 1.43 0.01 .mu.g/mL. | | Definition | ChEBI: Salvianolic acid A is a stilbenoid. | | General Description | Salvianolic acid A is a phenolic acid, isolated from Danshen, a traditional Chinese medicine, commonly used for the treatment of bone loss, chronic renal failure, hepatocirrhosis, hepatitis, coronary heart disease and cerebrovascular disease. | | Biochem/physiol Actions | Salvianolic acid A is cell protective antioxidant originally isolated from Salvia. It has been found to attenuate PDGF-induced ROS formation in hepatic stellate cells and protected against isoproterenol-induced myocardial damage in rats. |
| | Salvianolic acid Preparation Products And Raw materials |
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