Spirapril

Spirapril Basic information
Product Name:Spirapril
Synonyms:(8S-(7(R*(R*)),8R*))-7-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid;SPIRAPRIL;SPIRAPRIL FOR SYSTEM SUITABILITY EPY;SPIRAPRIL FOR SYSTEM SUITABILITY EPY(CRM STANDARD);1,4-Dithia-7-azaspiro(4,4)nonane-8-carboxylic acid, 7-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-, (8S-(7(R*(R*)),8R*))-;Brn 4277924;Espirapril;Espirapril [spanish]
CAS:83647-97-6
MF:C22H30N2O5S2
MW:466.61
EINECS:
Product Categories:
Mol File:83647-97-6.mol
Spirapril Structure
Spirapril Chemical Properties
Boiling point 697.8±55.0 °C(Predicted)
density 1.32±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka2.99±0.20(Predicted)
Safety Information
MSDS Information
Spirapril Usage And Synthesis
UsesSpirapril is an Angiotensin-converting enzyme inhibitor and used to treat high blood pressure.
DefinitionChEBI: Spirapril is a dipeptide, a dithioketal, an azaspiro compound, a dicarboxylic acid monoester, an ethyl ester, a tertiary carboxamide, a secondary amino compound and a pyrrolidinecarboxylic acid. It has a role as a prodrug, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and an antihypertensive agent. It is functionally related to a spiraprilat.
Spirapril Preparation Products And Raw materials
Raw materialsp-Toluenesulfonic acid-->1,2-Ethanedithiol-->Ethyl 2-oxo-4-phenylbutyrate
N-Acetyl-DL-ethionine L-Homophenylalanine ethyl ester hydrochloride 1,4-Dithia-7-aza-spiro[4.4]nonane hydrochloride Spiraprilat Carbonyl iron powder 3,4'-DIAMINODIPHENYLMETHANE ALTRENOGEST N-FORMYL-DL-ETHIONINE DL-HOMOPHENYLALANINE METHYL ESTER HYDROCHLORIDE L-Homophenylalanine ethyl ester SPIRAPRIL FOR SYSTEM SUITABILITY 1,4-DITHIA-7-AZA-SPIRO[4.4]NONANE Spiraprilat L-β-Homophenylalanine, HPLC 98% 2,2'-(ETHYLENEDIIMINO)-DIBUTYRIC ACID SPIRAPRIL HYDROCHLORIDE MONOHYDRATE AMINO ACIDS L-ETHIONINE

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