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| | SAQUINAVIR MESYLATE Basic information |
| Product Name: | SAQUINAVIR MESYLATE | | Synonyms: | RO 31-8959;SAQUINAVIR MESYLATE;INVIRASE;FORTOVASE;(2S)-N1[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2-(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide Mesylate;Ro 31-895;Butanediamide, N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, (2S)-, monomethanesulfonate (salt) (9CI);Butanediamide, N1-[3-[3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, [3S-[2[1R*(R*),2S*],3a,4ab,8ab]]-, monomethanesulfonate (salt) | | CAS: | 149845-06-7 | | MF: | C39H54N6O8S | | MW: | 766.95 | | EINECS: | | | Product Categories: | API;Anti-virals;Inhibitors;Intermediates & Fine Chemicals;Non-nucleoside Reverse Transcriptase;Pharmaceuticals;Active Pharmaceutical Ingredients;Anti-viral Compounds;Saquinavir | | Mol File: | 149845-06-7.mol |  |
| | SAQUINAVIR MESYLATE Chemical Properties |
| Melting point | 241 °C (decomp) | | storage temp. | 2-8°C | | solubility | DMSO: ≥5mg/mL | | form | powder | | color | white to tan | | InChIKey | IRHXGOXEBNJUSN-YOXDLBRISA-N | | CAS DataBase Reference | 149845-06-7(CAS DataBase Reference) |
| WGK Germany | 3 | | HS Code | 2933492250 | | Toxicity | monkey,LD,oral,> 1680mg/kg (1680mg/kg),Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 40, Pg. 2183, 1998. |
| | SAQUINAVIR MESYLATE Usage And Synthesis |
| Chemical Properties | White Crystalline Solid | | Uses | A selective HIV protease inhibitor. Antiviral. | | Uses | Antiviral;Protease inhibitor | | Uses | Saquinavir mesylate may be used in cell signaling and immunology studies. | | Definition | ChEBI: Saquinavir mesylate is an organic molecular entity. | | Brand name | Invirase (Roche). | | General Description | Saquinavir is a peptidomimetic hydroxyethylamine inhibitor, which is used to treat human immunodeficiency virus (HIV) infection. | | Hazard | Moderately toxic by ingestion. | | Biochem/physiol Actions | Saquinavir is an HIV Protease Inhibitor used in antiretroviral therapy. It inhibits both HIV-1 and HIV-2 proteases. Studies have also looked at saquinavir as a possible anti-cancer agent. | | storage | Store at +4°C |
| | SAQUINAVIR MESYLATE Preparation Products And Raw materials |
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