ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Pyridine derivatives 2-Hydroxy-5-pyridinecarboxylic acid

2-Hydroxy-5-pyridinecarboxylic acid

2-Hydroxy-5-pyridinecarboxylic acid Basic information
Product Name:2-Hydroxy-5-pyridinecarboxylic acid
Synonyms:TIMTEC-BB SBB004181;1,6-dihydro-6-oxo-3-pyridinecarboxylicaci;SPECS AI-942/25034174;2-HYDROXY-5-PYRIDINECARBOXYLIC ACID;2-HYDROXYPYRIDINE-5-CARBOXYLIC ACID;5-CARBOXY-2(1H)-PYRIDINONE;6-HYDROXY-3-PYRIDINECARBOXYLIC ACID;6-HYDROXYNICOTINIC ACID
CAS:5006-66-6
MF:C6H5NO3
MW:139.11
EINECS:225-682-9
Product Categories:Aromatics;Heterocycles;Nitrogen cyclic compounds;blocks;Organic acids;Nicotine Derivatives;Carboxes;Pyridines;Pyridine
Mol File:5006-66-6.mol
2-Hydroxy-5-pyridinecarboxylic acid Structure
2-Hydroxy-5-pyridinecarboxylic acid Chemical Properties
Melting point >300 °C (lit.)
Boiling point 255.04°C (rough estimate)
density 1.4429 (rough estimate)
refractive index 1.5423 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Powder
pka3.80±0.50(Predicted)
color Off-white to light brown
BRN 472182
InChIInChI=1S/C6H5NO3/c8-5-2-1-4(3-7-5)6(9)10/h1-3H,(H,7,8)(H,9,10)
InChIKeyBLHCMGRVFXRYRN-UHFFFAOYSA-N
SMILESC1NC(=O)C=CC=1C(O)=O
CAS DataBase Reference5006-66-6(CAS DataBase Reference)
EPA Substance Registry System6-Hydroxynicotinic acid (5006-66-6)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
WGK Germany 3
TSCA T
HazardClass IRRITANT
HS Code 29333990
MSDS Information
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2-Hydroxy-5-pyridinecarboxylic acid English
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2-Hydroxy-5-pyridinecarboxylic acid Usage And Synthesis
Chemical PropertiesOff-white powder
Uses6-Hydroxynicotinic acid is used as building block in chemical synthesis.
UsesNicotinic Acid derivative, found in fruit hypanthium.
UsesMetabolite of nicotinamide. Stimulates adrenocortical secretion
DefinitionChEBI: A monohydroxypyridine that is the 6-hydroxy derivative of nicotinic acid.
General Description6-Hydroxypyridine-3-carboxylic acid (6-Hydroxynicotinic acid) reacts with Ln(2)O(3) (Ln = Nd, Sm, Eu, Gd) and oxalic acid (H(2)OX) to generate four novel lanthanide-organic coordination polymeric networks.
Purification MethodsIt crystallises from water with m 303.4-303.7o(dec), or with m 325o(dec) from aqueous EtOH. The methyl ester crystallises from Me2CO with m 166o and pK2 0 9.92. [Albert J Chem Soc 1020 1960, Beilstein 22 III/IV 2147, 22/6 V 119.]
5-CHLORO-6-HYDROXY-3-PYRIDINECARBOXYLIC ACID 6-HYDROXY-5-(2-HYDROXYBENZOYL)-2-(TRIFLUOROMETHYL)NICOTINIC ACID 2,6-Dimethoxypyridine-3-carboxylic acid METHYL 1-(2,6-DICHLOROBENZYL)-6-OXO-1,6-DIHYDRO-3-PYRIDINECARBOXYLATE METHYL 2,7-DIMETHYL-5-OXO-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLATE 2,7-DIMETHYL-5-OXO-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID METHYL 2-(METHOXYMETHYL)-7-METHYL-5-OXO-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLATE 1-BENZYL-6-OXO-1,6-DIHYDRO-3-PYRIDINECARBOXYLIC ACID 2-Hydroxy-5-pyridinecarboxylic acid 2,6-DIHYDROXY-4-METHYL-NICOTINIC ACID ETHYL 2-[2-(3,5-DICHLOROANILINO)VINYL]-5-OXO-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLATE ETHYL 2,7-DIMETHYL-5-OXO-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLATE 6-OXO-1-[3-(TRIFLUOROMETHYL)BENZYL]-1,6-DIHYDRO-3-PYRIDINECARBOXYLIC ACID METHYL 2-ETHYL-7-METHYL-5-OXO-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLATE 2-METHYL-10-OXO-10H-9-OXA-1-AZA-ANTHRACENE-3-CARBOXYLIC ACID METHYL ESTER METHYL 1-(3,4-DICHLOROBENZYL)-6-OXO-1,6-DIHYDRO-3-PYRIDINECARBOXYLATE METHYL 2-(METHOXYMETHYL)-5-OXO-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLATE METHYL 6-OXO-1-[3-(TRIFLUOROMETHYL)BENZYL]-1,6-DIHYDRO-3-PYRIDINECARBOXYLATE
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