2,6-Difluorophenylboronic acid

2,6-Difluorophenylboronic acid Basic information

Product Name:	2,6-Difluorophenylboronic acid
Synonyms:	BORONICACID, B-(2,6-DIFLUOROPHENYL)-;2,6-Difluorophenylboronic acid 98%;RARECHEM AH PB 0108;CHEMBRDG-BB 3200972;AKOS BRN-0261;AKOS BRN-0146;2,6-DIMETHOXYBENZENEBORONIC ACID;2,6-DIFLUORO PHENYLBORIC ACID
CAS:	162101-25-9
MF:	C6H5BF2O2
MW:	157.91
EINECS:	627-874-1
Product Categories:	Organometallic Reagents;Boronate Ester;Aryl Boronic Acids;Boronic Acids and Derivatives;Potassium Trifluoroborate;Pyridines;Substituted Boronic Acids;Fluorobenzene;Boronic Acid;Aryl;Halogenated;Organoborons;Chemical Synthesis;Disubstituted Aryl Boronic Acids;HALIDE;blocks;BoronicAcids;FluoroCompounds;B (Classes of Boron Compounds);Boronic Acids;Boronic Acids;Boronic Acids and Derivatives
Mol File:	162101-25-9.mol

2,6-Difluorophenylboronic acid Chemical Properties

Melting point	147-149 °C (lit.)
Boiling point	260.1±50.0 °C(Predicted)
density	1.35±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in methanol.
pka	8.12±0.58(Predicted)
form	solid
color	White to Almost white
BRN	8545931
InChIKey	DBZAICSEFBVFHL-UHFFFAOYSA-N
CAS DataBase Reference	162101-25-9(CAS DataBase Reference)

Safety Information

MSDS Information

2,6-Difluorophenylboronic acid Usage And Synthesis

Chemical Properties	White to off-white crystalline powder
Uses	suzuki reaction
Uses	2,6-Difluorophenylboronic acid can be used: As a substrate in the model reaction of Suzuki–Miyaura coupling with?4-chloro-3-methylanisole. To prepare 4-bromo-2,3′,5′,6-tetrafluorobiphenyl, a key intermediate for the synthesis of 2,6-difluorinated oligophenyls applicable in organic semiconductors. To prepare ethyl 4-(2,6-difluorophenyl)nicotinate, a key intermediate for the synthesis of 4-phenyl pyridine based potent TGR5 agonists.
Uses	Intermediates of Liquid Crystals

2,6-Difluorophenylboronic acid Preparation Products And Raw materials

Raw materials	Diethyl ether-->n-Butyllithium-->Triisopropyl borate-->1-Bromo-2,6-difluorobenzene-->Water-->Trimethyl borate-->1,3-Difluorobenzene
Preparation Products	2,6-Difluorophenol-->2-(2,6-Difluorophenyl)-3-Fluoro-6-Methylpyridine(WXC02866)-->4-(2,6-Difluorophenyl)phenol

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